Chronic periodontitis
MONDO:0005593A chronic inflammatory process that affects the tissues that surround and support the teeth.
Also known as: periodontitis, chronic
145 clinical trials for this condition and its sub-types, 65 tagged with Chronic periodontitis itself.
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Sub-types of Chronic periodontitis
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Chronic apical periodontitis 55 trials
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Periodontitis, chronic, adult 14 trials
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Periodontitis, aggressive 4 trials · 6 incl. sub-types
2 sub-types
- Periodontitis, aggressive 1 6 trials
- Periodontitis, aggressive, 2 0 trials
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A tiny camera could make gum surgery more precise
Disease control OngoingThis pilot study tests whether using a videoscope—a small camera that gives surgeons a magnified, clearer view—during minimally invasive gum surgery improves outcomes for people with severe chronic periodontitis. Participants are randomly assigned to receive surgery with the vide…
Sponsor: University of Illinois at Chicago • Aim: Disease control
Last updated Aug 19, 2026 00:00 UTC
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Gentle gum therapy could heal bone defects without surgery
Disease control CancelledThis study tests a minimally-invasive non-surgical therapy (MINST) for treating gum disease-related bone defects. The approach uses small instruments and magnification to clean deep gum pockets with less tissue damage than traditional surgery. Researchers will measure bone healin…
Sponsor: Queen Mary University of London • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Your own tooth could fix your gum disease bone loss
Disease control By invitation onlyThis study tests whether using a patient's own extracted tooth as a bone graft works as well as a traditional bone graft to repair bone damage from severe gum disease. Sixty adults with chronic periodontitis will receive one of the two graft types, both combined with a healing ge…
Sponsor: Semmelweis University • Aim: Disease control
Last updated Jun 27, 2026 12:24 UTC
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Gum disease breakthrough? blood concentrate shows promise in small trial
Disease control OngoingThis study tested whether adding injectable Platelet-Rich Fibrin (i-PRF), a natural concentrate from a patient's own blood, to standard deep cleaning improves gum disease outcomes. In 13 adults with moderate to severe periodontitis, one side of the mouth received the combined tre…
Sponsor: Al-Mustansiriyah University • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC
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Gum surgery showdown: one flap or two?
Disease control OngoingThis study compares two types of minimally invasive gum surgery for treating deep pockets caused by periodontitis. Fifty adults with advanced gum disease will be randomly assigned to receive either a single-flap or double-flap procedure. Researchers will measure how well each tec…
Sponsor: University of Campinas, Brazil • Aim: Disease control
Last updated Jun 27, 2026 08:13 UTC
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Your own blood could help heal gum disease bone loss
Disease control OngoingThis study tests whether adding a concentrate from the patient's own blood (injectable platelet rich fibrin, or I-PRF) to a standard bone graft helps repair bone defects caused by advanced gum disease. Twenty adults with stage III periodontitis and deep gum pockets will receive e…
Sponsor: Al-Azhar University • Aim: Disease control
Last updated Jun 27, 2026 08:00 UTC
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Scientists hunt for genetic clues linking gum disease and heart trouble
Knowledge-focused OngoingThis study looks at two genetic markers (Cofilin-2 and Lactoferrin) in 84 adults with gum disease, some of whom also have coronary heart disease. Researchers measure changes in these markers and gum health after a standard deep-cleaning dental treatment. The goal is to better und…
Sponsor: Meenakshi Ammal Dental College and Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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Could antidepressants soothe your gums? new study investigates
Knowledge-focused OngoingThis study looks at whether taking antidepressants can reduce gum inflammation in people with chronic periodontitis (gum disease) and depression. Researchers will collect gum fluid and plaque samples from 92 patients during routine dental procedures. The goal is to see if depress…
Sponsor: University of Alabama at Birmingham • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC