Could antidepressants soothe your gums? new study investigates
NCT ID NCT03553095
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at whether taking antidepressants can reduce gum inflammation in people with chronic periodontitis (gum disease) and depression. Researchers will collect gum fluid and plaque samples from 92 patients during routine dental procedures. The goal is to see if depression medication lowers inflammatory markers in the mouth.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could point toward using antidepressants to help treat gum disease in people with depression.
What could go wrong
This is a small observational study, not a treatment trial. It may not prove that antidepressants directly reduce inflammation, and results may not apply to everyone.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for DEPRESSION are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Unversity of Alabama at Birmingham, School of Dentistry
Birmingham, Alabama, 35294-0007, United States