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Chronic intestinal failure
MONDO:0017418Chronic intestinal failure (CIF) is a chronic type of intestinal failure characterized by a nonfunctioning small bowel (that may be reversible or irreversal) where the body is unable to maintain energy and nutritional needs through absorption of food or nutrients via the intestinal tract (despite being metabolically stable) and which therefore necessitates long-term parenteral feeding. CIF may be the result of congenital digestive diseases (such as gastroschisis, atresia of small intestine), short bowel syndrome, intra-abdominal or pelvic cancer, or progressive and devastating gastrointestinal or systemic benign diseases (such as Crohn disease).
Also known as: CIF
25 clinical trials for this condition and its sub-types.
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New study tracks hidden sugar damage in patients on IV nutrition
Knowledge-focused Not yet recruitingThis observational study will follow 50 adults and children who are starting long-term parenteral nutrition (IV nutrition) to measure the buildup of advanced glycation end-products (AGEs) in their skin. AGEs are harmful compounds that form when sugar binds with proteins, and they…
Phase: NA • Sponsor: University Hospital, Bordeaux • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Can online doctor training improve life for intestinal failure patients?
Knowledge-focused Not yet recruitingThis study tests a virtual education program called LIFT-ECHO, where non-specialist doctors learn from experts how to better manage chronic intestinal failure. Researchers will enroll 150 patients and their doctors, tracking quality of life and disease activity over 12 months. Th…
Phase: NA • Sponsor: Icahn School of Medicine at Mount Sinai • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Timing matters: study seeks best moment to check liver health in short bowel patients
Knowledge-focused Not yet recruitingThis study looks at how receiving parenteral nutrition (IV feeding) changes the results of a liver stiffness test called FibroScan in people with short bowel syndrome. Researchers will measure liver stiffness before, during, and after the infusion in 20 stable adult patients. The…
Sponsor: Rigshospitalet, Denmark • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC
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New study to track hidden salt and mineral imbalances in sick kids
Knowledge-focused Not yet recruitingThis study will look at 150 infants and children aged 1 month to 4 years who are admitted to a hospital gastroenterology unit with a gastrointestinal disease. The goal is to find out how common electrolyte disturbances (like low sodium or potassium) are in these children. By meas…
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Jun 26, 2026 12:41 UTC