Chronic intestinal failure
MONDO:0017418Chronic intestinal failure (CIF) is a chronic type of intestinal failure characterized by a nonfunctioning small bowel (that may be reversible or irreversal) where the body is unable to maintain energy and nutritional needs through absorption of food or nutrients via the intestinal tract (despite being metabolically stable) and which therefore necessitates long-term parenteral feeding. CIF may be the result of congenital digestive diseases (such as gastroschisis, atresia of small intestine), short bowel syndrome, intra-abdominal or pelvic cancer, or progressive and devastating gastrointestinal or systemic benign diseases (such as Crohn disease).
Also known as: CIF
23 clinical trials for this condition and its sub-types.
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Muscle loss in intestinal failure: could a simple protein and workout combo turn the tide?
Disease control Not yet recruitingThis trial tests whether adding whey protein supplements, resistance training, or both can improve muscle mass in adults with chronic intestinal failure and low muscle mass. Participants receive standard nutritional support and are randomly assigned to one of four groups: usual c…
Sponsor: Wang Xinying • Aim: Disease control
Last updated Aug 14, 2026 00:00 UTC
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Can online doctor training improve life for intestinal failure patients?
Knowledge-focused Not yet recruitingThis study tests a virtual education program called LIFT-ECHO, where non-specialist doctors learn from experts how to better manage chronic intestinal failure. Researchers will enroll 150 patients and their doctors, tracking quality of life and disease activity over 12 months. Th…
Sponsor: Icahn School of Medicine at Mount Sinai • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Timing matters: study seeks best moment to check liver health in short bowel patients
Knowledge-focused Not yet recruitingThis study looks at how receiving parenteral nutrition (IV feeding) changes the results of a liver stiffness test called FibroScan in people with short bowel syndrome. Researchers will measure liver stiffness before, during, and after the infusion in 20 stable adult patients. The…
Sponsor: Rigshospitalet, Denmark • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC