Cholesteatoma of middle ear
MONDO:0006533A non-neoplastic lesion characterized by the proliferation of keratinizing squamous epithelium in the middle ear that results in the accumulation of keratin and cells. It is usually caused by repeated infections. If left untreated, it may increase in size and destroy the adjacent delicate bones of the middle ear.
Also known as: Epidermosis of ear, Epidermosis of middle ear, cholesteatoma (disease) of middle ear, cholesteatoma of middle ear, cholesteatoma of middle ear and mastoid, cholesteatoma of the middle ear, middle ear cholesteatoma, middle ear cholesteatoma (disease)
13 clinical trials for this condition and its sub-types.
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Broader categories
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New $50 hearing gadget could bring ear checks to remote villages
Diagnosis CompletedThis study tested a low-cost, smartphone-connected device that checks middle ear health. Researchers compared it to standard equipment in 30 adults and children. The goal is to make ear screening affordable and easy for rural communities, reducing preventable hearing loss.
Sponsor: University of Arkansas • Aim: Diagnosis
Last updated Jun 27, 2026 08:10 UTC
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Can a cheap drug make ear surgery safer and faster?
Symptom relief CompletedThis study tested whether a low dose of tranexamic acid, a drug that helps blood clot, could reduce bleeding during middle ear surgery. 100 adults undergoing microscopic or endoscopic ear surgery received either the drug or a placebo. The goal was to see if the drug improved the …
Phase: NA • Sponsor: TC Erciyes University • Aim: Symptom relief
Last updated Jun 26, 2026 14:29 UTC
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AI could cut skin specialist wait times, study hints
Knowledge-focused CompletedThis study tested an artificial intelligence algorithm designed to help primary care doctors decide whether a patient with a skin condition really needs to see a dermatologist. Researchers enrolled 200 adults with skin problems and had their doctors take photos of the affected ar…
Sponsor: AI Labs Group S.L • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC