Cholera
MONDO:0015766Cholera is an infectious disease, caused by intestinal infection with Vibrio cholerae, characterized by massive watery diarrhea and severe dehydration that can lead to shock and death if left untreated.
Also known as: Vibrio cholerae caused disease or disorder, Vibrio cholerae disease or disorder, Vibrio cholerae infectious disease, cholera due to Vibrio cholerae, Vibrio cholerae infection
16 clinical trials for this condition and its sub-types.
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Cholera vaccine vaxchora put to the test in immune response study
⭐️ VACCINE ⭐️ CompletedThis phase 2 trial tested the oral cholera vaccine Vaxchora in 34 healthy adults to see how well it triggers protective antibodies and immune cells. Participants received a single dose, and researchers measured antibody levels, B cells, and T cell responses. The goal is to unders…
Phase: PHASE2 • Sponsor: Emory University • Aim: ⭐️ VACCINE ⭐️
Last updated Jun 27, 2026 09:04 UTC
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New cholera drug could cut antibiotic use and hospital stays
Disease control CompletedThis study tested a new drug called VR-AD-1005 for treating severe diarrhea caused by cholera. The drug aims to reduce fluid loss and the need for antibiotics, which could help fight antibiotic resistance. 150 adults with cholera took part, and researchers measured stool output a…
Phase: PHASE2 • Sponsor: Hunazine Biotech S.L. • Aim: Disease control
Last updated Jun 27, 2026 13:01 UTC
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Could adding calcium to ORS stop diarrhea faster?
Disease control CompletedThis study tested whether an oral rehydration solution (ORS) with added calcium works better than standard ORS for adults with severe watery diarrhea, including cholera. Researchers measured stool output, diarrhea duration, and other symptoms in 396 adults. The goal is to find a …
Phase: PHASE2, PHASE3 • Sponsor: University of Florida • Aim: Disease control
Last updated Jun 27, 2026 12:07 UTC
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One dose, big hope: antibiotic may stop cholera in kids
Prevention CompletedThis trial tests whether giving children a single dose of the antibiotic azithromycin right after a household member tests positive for cholera can prevent them from getting infected. The study enrolls children aged 1 to 15 who share cooking facilities with a cholera patient. Res…
Phase: PHASE2 • Sponsor: Massachusetts General Hospital • Aim: Prevention
Last updated Aug 09, 2026 00:00 UTC