Cerebrospinal fluid leak
MONDO:0043327Discharge of cerebrospinal fluid through a hole through the skull bone most commonly draining from the nose (CEREBROSPINAL FLUID RHINORRHEA) or the ear (CEREBROSPINAL FLUID OTORRHEA).
Also known as: cerebrospinal fluid leak, CSF leak, CSF otorrhea, CSF rhinorrhea, Drainages, cerebrospinal fluid, Leakages, cerebrospinal fluid, Leaks, cerebrospinal fluid, cerebrospinal fluid Drainages
17 clinical trials for this condition and its sub-types.
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Broader categories
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Can a new patch seal the Brain's protective lining and stop leaks?
Disease control Not yet recruitingThis trial tests whether ArtiFix®, a synthetic sealant graft, can safely and effectively prevent cerebrospinal fluid leaks after cranial and spine surgery. About 228 adults scheduled for such surgeries will be randomly assigned to receive either ArtiFix® or standard care. Partici…
Phase: NA • Sponsor: Nurami Medical Ltd • Aim: Disease control
Last updated Aug 16, 2026 00:00 UTC
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Bed rest debate: shorter may be better for skull base surgery recovery
Knowledge-focused Not yet recruitingThis study looks at how many days of bed rest are best after a specific type of brain surgery done through the nose. About 316 adults having this surgery will be placed into groups with different bed rest times (0, 1, 2, or 3 days). The goal is to see which rest period leads to t…
Phase: NA • Sponsor: The Affiliated Hospital of Qingdao University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC
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New study aims to predict fluid drainage after back surgery
Knowledge-focused Not yet recruitingThis study looks at 326 adults aged 18-80 who need long-segment spine surgery (two or more vertebrae). Researchers want to find out what factors, like belly fat thickness, can predict how much fluid will drain after surgery. The goal is to help surgeons decide who needs a drain a…
Sponsor: AKİF BULUT • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC