Cerebral sinovenous thrombosis
MONDO:0017993A rare but serious cerebrovascular disorder involving thrombosis of the cerebral venous system. It affects children from the newborn period through childhood and adolescence. In childhood CSVT, acute infections of the head and neck such as mastoiditis are most common, followed by chronic underlying diseases such as nephrotic syndrome, cancer, and inflammatory bowel disease. Signs and symptoms are also age related. Seizures and altered mental status are the commonest manifestations in newborns. Headache, vomiting, and lethargy, sometimes with 6th nerve palsy, are the most common symptoms in children and adolescents.
Also known as: CSVT
25 clinical trials for this condition and its sub-types.
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New hope for kids with rare brain clots: blood thinner pill tested
Disease control CompletedThis study compared the safety and effectiveness of the oral blood thinner rivaroxaban against standard anticoagulants in 75 children (ages 2 months to 18 years) with cerebrosinovenous thrombosis (CSVT), a rare type of brain vein clot. The goal was to see if rivaroxaban could nor…
Phase: NA • Sponsor: Muhammad Aamir Latif • Aim: Disease control
Last updated Jun 27, 2026 12:06 UTC
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Eye ultrasound could replace needles for measuring brain pressure in kids
Diagnosis CompletedThis study tested whether an ultrasound of the optic nerve sheath (the lining around the nerve connecting the eye to the brain) can accurately detect dangerously high pressure inside the skull in children. Researchers measured the nerve sheath diameter in 230 children with brain …
Phase: NA • Sponsor: Hospices Civils de Lyon • Aim: Diagnosis
Last updated Jun 26, 2026 13:26 UTC
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Blood tests may help predict recovery in rare brain clot condition
Knowledge-focused CompletedThis study looked at 232 people with cerebral venous thrombosis, a rare stroke that mainly affects young women. Researchers took blood samples at several time points to measure markers of clot formation and breakdown. They wanted to see if these markers relate to how the disease …
Phase: NA • Sponsor: University Hospital, Rouen • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:35 UTC