Cerebral amyloid angiopathy
MONDO:0005620Hereditary cerebral hemorrhage with amyloidosis (HCHWA) describes a group of rare familial central nervous system disorders characterized by amyloid deposition in the cerebral blood vessels leading to hemorrhagic and non-hemorrhagic strokes, focal neurological deficits, and progressive cognitive decline eventually leading to dementia.
Also known as: HCHWA, dutch hereditary cerebral amyloid angiopathy, hereditary cerebral haemorrhage with amyloidosis - Dutch type, hereditary cerebral hemorrhage with amyloidosis - Dutch type, CAA, familial, cerebral amyloid angiopathy, familial, cerebral amyloid angiopathy, genetic
30 clinical trials for this condition and its sub-types, 16 tagged with Cerebral amyloid angiopathy itself.
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Sub-types of Cerebral amyloid angiopathy
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ACys amyloidosis 1 trial
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Cerebral amyloid angiopathy, APP-related 0 trials · 1 incl. sub-types
6 sub-types
- ABeta amyloidosis, dutch type 1 trial
- ABeta amyloidosis, Arctic type 0 trials
- ABeta amyloidosis, Iowa type 0 trials
- ABeta amyloidosis, Italian type 0 trials
- ABetaA21G amyloidosis 0 trials
- ABetaL34V amyloidosis 0 trials
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ABri amyloidosis 0 trials
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ADan amyloidosis 0 trials
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Can olive oil and walnuts shield the brain from stroke and memory loss?
Disease control Recruiting nowThis trial tests whether a Mediterranean diet, enriched with extra virgin olive oil or walnuts, can lower the chance of stroke and slow cognitive decline in people with cerebral amyloid angiopathy (CAA) or CADASIL, two conditions that affect blood vessels in the brain. Participan…
Sponsor: Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta • Aim: Disease control
Last updated Sep 03, 2026 00:00 UTC
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Ancient herb mix takes on brain bleed: can it stop repeat strokes?
Disease control Recruiting nowThis study tests a traditional Chinese medicine called Jiedu Huayu oral prescription in 436 people who have had a brain bleed due to a condition called cerebral amyloid angiopathy. The goal is to see if the herbal treatment can lower the chance of having another stroke or blood v…
Phase 3 • Sponsor: Beijing Tiantan Hospital • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
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Eye injection could spot hidden brain bleeding risk
Diagnosis Recruiting nowThis study tests a dye called AMDX-2011P that is injected into the vein to see if it can light up amyloid deposits in the retina, which may indicate cerebral amyloid angiopathy (CAA), a condition that raises the risk of brain bleeding. About 25 adults with CAA will receive a sing…
Phase 2 • Sponsor: Amydis Inc. • Aim: Diagnosis
Last updated Jun 27, 2026 09:04 UTC
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Your digital twin could help prevent another stroke
Knowledge-focused Recruiting nowThis small study tests a smartphone app that creates a 'digital twin' of the patient to help manage health after a stroke, moyamoya disease, or cerebral amyloid angiopathy. Twenty adults will either use the app plus standard care, or standard care alone. The goal is to see if pat…
Sponsor: Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta • Aim: Knowledge-focused
Last updated Aug 30, 2026 00:00 UTC
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500-Patient study aims to unlock secrets of brain bleeding disease
Knowledge-focused Recruiting nowThis study is collecting medical data and brain scans from 500 people with cerebral amyloid angiopathy (CAA), a condition that causes bleeding in the brain and memory problems in older adults. Researchers want to better understand how the disease progresses and find markers that …
Sponsor: Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:02 UTC