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Eye injection could spot hidden brain bleeding risk

NCT ID NCT05709314

Recruiting now Diagnosis Sponsor: Amydis Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a dye called AMDX-2011P that is injected into the vein to see if it can light up amyloid deposits in the retina, which may indicate cerebral amyloid angiopathy (CAA), a condition that raises the risk of brain bleeding. About 25 adults with CAA will receive a single dose and be monitored for safety and how well the dye works. The goal is to develop a simple eye exam as a non-invasive way to diagnose CAA.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
AMDX-2011P (a dye injected into the vein to detect amyloid deposits in the retina)
What this could lead to
If successful, this could lead to a simple eye test to diagnose cerebral amyloid angiopathy (CAA), a brain blood vessel condition, without needing invasive procedures.
What could go wrong
This is an early Phase 2 trial with only 25 participants, so results may not apply to everyone. The dye might not reliably detect amyloid in the retina, or safety issues could arise.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cerebral amyloid angiopathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CEREBRAL AMYLOID ANGIOPATHY

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • Associated Retina Consultants

    RECRUITING

    Phoenix, Arizona, 85020, United States

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