ABri amyloidosis
MONDO:0008306A cerebral amyloid angiopathy characterized by onset in the 4th to 6th decade of life, progressive mental deterioration, spasticity, muscular rigidity but no tremors, spontaneous movements or sensory changes that has material basis in an autosomal dominant mutation of ITM2B on chromosome 13q14.2.
Also known as: ABri amyloidosis, FBD, cerebral amyloid angiopathy, British type, cerebral amyloid angiopathy, ITM2B-related, type 1, familial dementia, British type, presenile dementia with spastic ataxia, Bri amyloidosis, ITM2B-related cerebral amyloid angiopathy 1
14 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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New stomach drug could shield heart patients from bleeding
Disease control Recruiting nowThis study compares two stomach-acid-lowering drugs—tegoprazan and rabeprazole—in about 3,300 heart disease patients who take blood thinners and are at high risk for stomach bleeding. The goal is to see if tegoprazan works as well as rabeprazole at preventing serious gut problems…
Phase: PHASE4 • Sponsor: Duk-Woo Park, MD • Aim: Disease control
Last updated Jun 28, 2026 00:00 UTC
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App-Based diet tracking tested in rare disease
Knowledge-focused Recruiting nowThis pilot trial is testing whether amyloidosis patients can use the MyFitnessPal smartphone app to track their daily food and supplement intake for 8 weeks. The goal is to see if this low-cost method is feasible for studying malnutrition and weight loss in this condition. Forty …
Phase: NA • Sponsor: Barbara Ann Karmanos Cancer Institute • Aim: Knowledge-focused
Last updated Jun 28, 2026 00:00 UTC
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Massive korean registry to unlock secrets of heart and stroke
Knowledge-focused Recruiting nowThis study is building a huge database of up to 800,000 Korean patients with heart or brain vascular disease. By tracking their health over many years, researchers hope to understand the unique patterns and risk factors in this population. The goal is to create a platform that ca…
Sponsor: Samsung Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:25 UTC
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New stroke registry aims to unlock secrets of brain damage
Knowledge-focused Recruiting nowThis study collects blood, clots, and tissue from up to 1000 people having procedures for stroke or other blood vessel problems in the brain. Researchers will analyze these samples to find biological markers and understand inflammation. The goal is to learn more about how stroke …
Sponsor: Justin Fraser • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:10 UTC
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New biobank aims to unlock secrets of rare amyloidosis
Knowledge-focused Recruiting nowThis study is creating a biobank and data registry for people with amyloidosis, a rare disease where abnormal proteins build up in organs. Researchers will collect blood, urine, tissue samples, and medical information from 505 participants over time. The goal is to store these ma…
Sponsor: Universitaire Ziekenhuizen KU Leuven • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC
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New microscope gadget aims to give surgeons X-Ray vision during delicate operations
Knowledge-focused Recruiting nowThis study tests a special microscope attachment called GLOW800 that helps surgeons see blood flow and tissues in real time during brain and reconstructive surgery. About 29 adults will take part, and surgeons will rate how well the tool works. The goal is to confirm the device i…
Sponsor: Leica Microsystems (Schweiz) AG • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC
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Robot takes the joystick for brain surgery – first human test underway
Knowledge-focused Recruiting nowThis early study is testing whether a robot can help doctors perform delicate brain blood vessel procedures, such as angiography, embolization, and thrombectomy. Ten patients scheduled for these standard procedures will have them done using a robotic system instead. The main goal…
Phase: NA • Sponsor: Navigantis Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC
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Scientists launch massive amyloid sample collection
Knowledge-focused Recruiting nowThis study is creating a large collection of blood, urine, and tissue samples from up to 10,000 people with amyloid diseases (like multiple myeloma). The goal is to store these samples and health data for future research to better understand these conditions. Participants do not …
Sponsor: Boston Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC