Cardiogenic shock
MONDO:0800175A rare, cardiac condition characterized by severely decreased cardiac output, hypoperfusion and end-organ dysfunction, in the presence of adequate intravascular volume. The clinical presentation is variable and may range from subtle hemodynamic alterations to overt cardiovascular collapse. Commonly reported features include dyspnea, crackles, elevated jugular venous pressure, altered mental state, abnormal pulse pressure, oliguria, cold extremities, and increased serum lactate levels.
92 clinical trials for this condition and its sub-types.
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Could a diabetes drug help heart shock patients?
Disease control OngoingThis study looks at whether starting empagliflozin early in patients with cardiogenic shock (a severe heart pump failure) can reduce deaths and hospital readmissions within 3 months. Researchers compared 418 patients who received the drug plus usual care against those who got usu…
Sponsor: Central Hospital, Nancy, France • Aim: Disease control
Last updated Jun 27, 2026 09:11 UTC
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Could a simple pacemaker tweak help heart shock patients?
Symptom relief OngoingThis study tests whether increasing the backup pacing rate from 75 to 100 beats per minute improves blood flow in adults with cardiogenic shock who already have a permanent pacemaker. Twenty-five participants in the cardiac ICU will be exposed to both rates in random order, with …
Phase: NA • Sponsor: Vanderbilt University Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
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Can ultrasound guide septic shock treatment? experts weigh in
Knowledge-focused ENROLLING_BY_INVITATIONThis study gathers 35-50 international critical care experts to agree on how to classify and manage septic shock using point-of-care ultrasound. The goal is to create consensus statements that could help personalize treatment. No patients are enrolled; instead, experts complete s…
Sponsor: Albany Medical College • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Can better Decision-Making save heart attack victims in shock?
Knowledge-focused OngoingThis study looks at how doctors treat people having a severe heart attack complicated by cardiogenic shock, where the heart can't pump enough blood. Researchers will track 124 patients at 20 U.S. hospitals to see how decisions about using mechanical heart support devices affect s…
Sponsor: Henry Ford Health System • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:09 UTC
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Tiny study aims to Fine-Tune breathing machines for Heart-Lung bypass patients
Knowledge-focused ENROLLING_BY_INVITATIONThis study looks at how well air and blood mix in the lungs of 10 adults on a heart-lung bypass machine (VA ECMO). Researchers will adjust the breathing machine settings using special monitoring tools to see if they can improve oxygen levels. The goal is to gather information, no…
Phase: NA • Sponsor: Beth Israel Deaconess Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC