Capillary malformation

This phase 3 trial tests whether an experimental oral drug called engasertib can reduce the number of nosebleeds in adults with moderate to severe hereditary hemorrhagic telangiectasia (HHT), a genetic condition that causes abnormal blood vessels and frequent bleeding. About 240 …

This trial tests whether a liquid called Theravex can improve healing and stability when a dental implant is placed right after a tooth is pulled. Theravex is applied directly into the gap between the implant and the bone socket to stimulate bone growth. Researchers compare it to…

This study tests whether a rapamycin cream, applied after laser treatment, can improve the appearance of port wine stain birthmarks in children aged 10 and under. Thirty participants will receive laser therapy plus either a low or high dose of the cream or a placebo cream for 12 …

This phase 2 trial tests the drug everolimus in 67 people with vascular anomalies (abnormal blood vessels) that haven't responded to standard treatments. The goal is to shrink the lesions and improve symptoms. Participants take everolimus daily for 6 months, with doses adjusted b…

This study will test a special laser called the Vbeam Pro on 40 adults with rosacea or port-wine stain birthmarks. The goal is to see if the laser can safely clear or improve these red skin conditions. Participants will receive laser treatments and be evaluated for changes in app…

This study looks at how hereditary hemorrhagic telangiectasia (HHT) affects the quality of life of children and young adults aged 2 to 25. Participants will fill out questionnaires about their physical, emotional, and social well-being. Researchers will also review medical record…