Could a cream make laser treatment for birthmarks more effective?

NCT ID NCT07436611

First seen Jun 27, 2026 · Last updated Jul 01, 2026 · Updated 1 time

Summary

This study tests whether a rapamycin cream, applied after laser treatment, can improve the appearance of port wine stain birthmarks in children aged 10 and under. Thirty participants will receive laser therapy plus either a low or high dose of the cream or a placebo cream for 12 weeks. The goal is to see if the cream leads to greater fading than laser alone.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

rapamycin cream

What this could lead to

If it works, this could offer a better way to lighten port wine stain birthmarks by combining a cream with laser treatment.

What could go wrong

This is a small, early-phase trial with only 30 children. The cream may not improve results beyond laser alone, and skin irritation is possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

capillary hemangioma capillary malformation familial multiple nevi flammei

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Driscoll Children's Hospital

    Corpus Christi, Texas, 78411, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Sant Joan de Déu University Hospital

    Barcelona, Catalonia, 08950, Spain

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••