Could a cream make laser treatment for birthmarks more effective?

NCT ID NCT07436611

First seen Jun 27, 2026 · Last updated Jul 02, 2026 · Updated 2 times

Summary

This study tests whether a rapamycin cream, applied after laser treatment, can improve the appearance of port wine stain birthmarks in children aged 10 and under. Thirty participants will receive laser therapy plus either a low or high dose of the cream or a placebo cream for 12 weeks. The goal is to see if the cream leads to greater fading than laser alone.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
rapamycin cream
What this could lead to
If it works, this could offer a better way to lighten port wine stain birthmarks by combining a cream with laser treatment.
What could go wrong
This is a small, early-phase trial with only 30 children. The cream may not improve results beyond laser alone, and skin irritation is possible.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Driscoll Children's Hospital

    Corpus Christi, Texas, 78411, United States

  • Sant Joan de Déu University Hospital

    Barcelona, Catalonia, 08950, Spain

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