Brain hypoxia - ischemia
MONDO:0006685A disorder characterized by a reduction of oxygen in the blood combined with reduced blood flow (ischemia) to the brain from a localized obstruction of a cerebral artery or from systemic hypoperfusion. Prolonged hypoxia-ischemia is associated with ischemic attack, transient; brain infarction; brain edema; coma; and other conditions.
100 clinical trials for this condition and its sub-types.
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Cooling blankets tested to save newborn brains after oxygen loss
Disease control TerminatedThis study tested four different cooling treatments for newborns who suffered brain injury from lack of oxygen at birth. The treatments varied in how low the body temperature was lowered (33.5°C or 32.0°C) and how long cooling lasted (72 or 120 hours). The goal was to see which a…
Phase: NA • Sponsor: NICHD Neonatal Research Network • Aim: Disease control
Last updated Jun 27, 2026 14:03 UTC
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Tiny study probes how seizure meds affect brain wiring after injury
Knowledge-focused TerminatedThis pilot study aimed to see if antiseizure drugs like phenobarbital and levetiracetam change brain connectivity patterns in people with severe acute brain injury and reduced consciousness. Only 5 participants were enrolled before the study was terminated. Researchers used resti…
Phase: PHASE4 • Sponsor: University of North Carolina, Chapel Hill • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC