Bile duct cancer
MONDO:0003059A malignant neoplasm involving the bile duct
Also known as: bile duct tumor, bile duct tumour, bile duct cancer, cancer of bile duct, malignant bile duct neoplasm, malignant neoplasm of bile duct, malignant neoplasm of the extrahepatic bile duct
3354 clinical trials for this condition and its sub-types, 34 tagged with Bile duct cancer itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Bile duct cancer
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Bile duct carcinoma 20 trials · 454 incl. sub-types
4 sub-types
- Extrahepatic bile duct carcinoma 51 trials · 432 incl. sub-types Sub-types →
- Bile duct adenocarcinoma 17 trials · 419 incl. sub-types Sub-types →
- Bile duct carcinoma in situ 0 trials Sub-types →
- Squamous cell bile duct carcinoma 0 trials Sub-types →
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Malignant tumor of extrahepatic bile duct 1 trial · 434 incl. sub-types
3 sub-types
- Extrahepatic bile duct carcinoma 51 trials · 432 incl. sub-types Sub-types →
- Ampulla of vater cancer 5 trials · 69 incl. sub-types Sub-types →
- Extrahepatic bile duct sarcoma 0 trials Sub-types →
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Intrahepatic bile duct cancer 6 trials · 179 incl. sub-types
2 sub-types
- Intrahepatic cholangiocarcinoma 154 trials · 176 incl. sub-types Sub-types →
- Intrahepatic bile duct adenosquamous carcinoma 0 trials
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Bile duct sarcoma 0 trials
1 sub-type
Most studied deeper sub-types
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Which stent lasts longest? a Head-to-Head test for bile duct blockage
Disease control OngoingThis trial is testing three types of metal stents used to relieve jaundice in people with advanced cancer blocking the bile duct. The stents – uncovered, partially covered, or fully covered – are placed during an endoscopic procedure to keep the duct open. The study will compare …
Sponsor: Region Stockholm • Aim: Disease control
Last updated Aug 22, 2026 00:00 UTC
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New cocktail of drugs shows promise for Tough-to-Treat bile duct cancer
Disease control OngoingThis study tests a combination of four drugs (gemcitabine, cisplatin, quemliclustat, and zimberelimab) as a first treatment for people with advanced biliary tract cancers, including bile duct cancer. The goal is to see if this mix can slow cancer growth and help people live longe…
Phase 2 • Sponsor: Nataliya Uboha • Aim: Disease control
Last updated Aug 19, 2026 00:00 UTC
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Chemotherapy sprayed directly into the abdomen: a new attack on stubborn cancers
Disease control OngoingThis phase 1 trial tests a new method of delivering chemotherapy for people with cancers that have spread to the lining of the abdomen (peritoneal carcinomatosis) from gastrointestinal cancers like colorectal, stomach, or pancreatic cancer. The drug, nanoliposomal irinotecan (Oni…
Phase 1 • Sponsor: University Hospital, Ghent • Aim: Disease control
Last updated Jul 15, 2026 00:00 UTC
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New hope for bile duct cancer: targeted drug shows promise in early trial
Disease control OngoingThis study tests a drug called olaparib in 32 people with advanced bile duct cancer that has spread and has certain DNA repair gene mutations. Olaparib works by blocking enzymes that cancer cells need to grow. The main goal is to see how many patients are alive without their canc…
Phase 2 • Sponsor: Academic and Community Cancer Research United • Aim: Disease control
Last updated Jun 27, 2026 12:33 UTC
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Keytruda takes on 15 advanced cancers in major trial
Disease control OngoingThis phase 2 trial tests the immunotherapy drug pembrolizumab (Keytruda) in people with 15 types of advanced solid tumors that have worsened after standard treatments. About 1,600 participants receive the drug to see if their tumors shrink or stop growing. The study also looks fo…
Phase 2 • Sponsor: Merck Sharp & Dohme LLC • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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New stent study aims to ease jaundice in cancer patients
Symptom relief PausedThis study looks at whether a special stent (Hot AXIOS) can improve quality of life for people with bile duct blockages caused by cancer, when standard drainage fails. About 162 adults will receive the stent during an endoscopic procedure. The main goal is to see if jaundice symp…
Sponsor: Boston Scientific Corporation • Aim: Symptom relief
Last updated Sep 11, 2026 00:00 UTC