Autosomal dominant nonsyndromic hearing loss 2A
MONDO:0010817Any autosomal dominant nonsyndromic deafness in which the cause of the disease is a mutation in the KCNQ4 gene.
Also known as: DFNA2A, KCNQ4 autosomal dominant nonsyndromic deafness, autosomal dominant deafness 2A, autosomal dominant nonsyndromic deafness 2A, autosomal dominant nonsyndromic deafness caused by mutation in KCNQ4, autosomal dominant nonsyndromic deafness type 2A, deafness, autosomal dominant 2A, deafness, autosomal dominant 2a
60 clinical trials for this condition and its sub-types.
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New cochlear implant software aims to cut through noise
Symptom relief OngoingThis study tests new speech-enhancement software in cochlear implants to help adults with hearing loss understand speech better in noisy places. About 150 adult cochlear implant users will compare the new algorithms to the standard ones. The goal is to see if the new software imp…
Phase: NA • Sponsor: Cochlear • Aim: Symptom relief
Last updated Jun 27, 2026 12:38 UTC
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Brain training may boost hearing and thinking in older cochlear implant users
Symptom relief ENROLLING_BY_INVITATIONThis study tests whether an 8-week auditory-cognitive training program can improve speech recognition and cognitive function in older adults (60+) who have had a cochlear implant for 3 months to 3 years. Participants will do computer-based listening and thinking exercises at home…
Phase: NA • Sponsor: Gallaudet University • Aim: Symptom relief
Last updated Jun 27, 2026 12:02 UTC
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Can hearing aids and tinnitus maskers silence the ringing?
Symptom relief ENROLLING_BY_INVITATIONThis study is testing whether hearing aids alone or hearing aids with a tinnitus masker can improve hearing and reduce tinnitus symptoms in adults with hearing loss and tinnitus. One hundred participants will wear hearing aids for 6 months, with the masker turned on after 3 month…
Phase: NA • Sponsor: Starkey Laboratories, Inc • Aim: Symptom relief
Last updated Jun 27, 2026 08:07 UTC
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Ancient exercises may boost balance and mood in deaf community
Symptom relief ENROLLING_BY_INVITATIONThis study looks at whether traditional exercises like Tai Chi and Baduanjin can help people with hearing loss feel better physically and mentally. About 90 adults with severe hearing loss will be split into three groups: one doing Tai Chi, one doing Baduanjin, and one doing regu…
Phase: NA • Sponsor: Northeast Normal University • Aim: Symptom relief
Last updated Jun 27, 2026 08:01 UTC
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Massive gene hunt for deafness in pakistan could unlock new clues
Knowledge-focused ENROLLING_BY_INVITATIONThis study aims to find the genes that cause inherited hearing loss by analyzing DNA from 24,000 people in large Pakistani families. Researchers will compare affected and unaffected family members to identify new deafness genes. The goal is to improve genetic testing and counseli…
Sponsor: National Institute on Deafness and Other Communication Disorders (NIDCD) • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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New program helps parents of deaf kids handle behavior challenges
Knowledge-focused OngoingThis study looks at whether a special parent training program can help families with deaf or hard of hearing children aged 3 to 6. The program teaches positive parenting strategies to prevent behavior problems. About 295 parents will take part, and researchers will measure change…
Phase: NA • Sponsor: Christina Studts • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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Pupil dilation may reveal secrets of hearing nerve
Knowledge-focused ENROLLING_BY_INVITATIONThis study looks at how stimulating a nerve in the ear affects pupil size during cochlear implant surgery. Researchers will measure pupil dilation in 30 adults to learn more about the vagus nerve's role in hearing. The goal is to gather knowledge, not to treat hearing loss direct…
Phase: NA • Sponsor: NYU Langone Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Can remote check-ups replace clinic visits for cochlear implant patients?
Knowledge-focused OngoingThis study looks at whether managing cochlear implant care remotely (via phone or app) works as well as going to the clinic. About 148 adults with hearing loss will be followed for a year after their implant is activated. The goal is to see if remote care saves time and money whi…
Phase: NA • Sponsor: Cochlear • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC