Aspiration pneumonia

This study adapted a proven mouth care program for nursing homes to work in assisted living facilities for people with dementia. Nursing assistants were trained to provide daily mouth care and given supplies. The goal was to reduce harmful mouth bacteria that can lead to pneumoni…

This study tested whether using a special tongue brush (Orabrush) can lower the chance of aspiration pneumonia and improve swallowing in people who had a stroke. Researchers enrolled 252 stroke patients and compared those who used the brush to those who did not. The goal was to s…

This study is testing a portable, non-invasive breath analyzer that measures tiny particles in exhaled breath to screen for conditions like type 2 diabetes, liver disease, kidney disease, and lung disease. Researchers will enroll healthy volunteers and people with known diagnoses…

This study tested a new MRI technique that can take pictures of children's lungs without using radiation or injecting contrast dye. 72 children aged 6-16 had both a standard CT scan and this new MRI. The goal was to see if the MRI could produce clear images of the lungs, potentia…

This study looked at whether a simple oral hygiene routine could prevent a serious lung infection called aspiration pneumonia in people hospitalized after a stroke. Researchers compared 90 stroke patients who received structured mouth care from nurses to similar patients who got …

This study tested whether giving a small amount of s-ketamine during chest surgery could reduce the risk of postoperative delirium (sudden confusion) in patients aged 60 and older. Over 500 participants were randomly assigned to receive either s-ketamine or another drug (dexmedet…

This study tested freezing the nerves between the ribs during robot-assisted lung surgery to see if it reduces pain and the need for painkillers afterward. 33 adults having lung surgery were randomly assigned to get the nerve freeze or standard pain medicine. Researchers tracked …

This study looked at whether giving a low dose of a muscle relaxant (rocuronium) during bronchoscopy—a procedure where a tube is inserted into the lungs—could reduce complications like throat spasms and coughing. 153 adults having elective bronchoscopy were split into two groups:…

This study looked at immune cells called alveolar macrophages in the lungs of 18 people with non-infectious lung diseases. Researchers used a technique called flow cytometry to study the surface proteins on these cells. The goal was to better understand the role of these cells in…

This completed study looked at 104 adults in the ICU with severe pneumonia caused by three common bacteria. Researchers checked whether the bacteria were sensitive to amoxicillin/clavulanic acid (AMC) or to third-generation cephalosporins (3GC), which are standard treatments. The…

This study looks at why some people develop pneumonia after accidentally inhaling food, drink, or stomach contents. Researchers will track patients in intensive care and general medicine who have had a known or suspected inhalation event. The goal is to identify risk factors and …

This study looked at whether a quick stomach ultrasound before emergency surgery can help doctors choose the safest way to place a breathing tube. In 43 adult emergency patients, doctors used ultrasound to measure stomach contents and then decided on the airway method. The goal w…

This study used ultrasound to measure stomach contents in 94 patients before surgery, comparing those on semaglutide (a GLP-1 drug for diabetes/weight loss) to those not taking it. The goal was to see if semaglutide increases the risk of a 'full stomach' despite following fasting…

This study looked at 93 people with lung disease who get short of breath when active. Participants did two 6-minute walk tests: one at their fastest pace and one at their normal walking speed. The goal was to see if the normal-speed test gives a more accurate picture of when they…

This study observed 91 ICU patients on breathing machines who needed a tracheostomy (a tube in the windpipe). One group continued receiving liquid food through a feeding tube until just before the procedure, while the other group fasted for 6-8 hours as usual. Researchers tracked…

This study looked at over 10,000 people who had a gastrointestinal endoscopy (a scope procedure for the stomach or colon) under sedation. The goal was to find out how often breathing complications like cough, fever, or shortness of breath happen afterward, and what factors might …

This study tested whether a rapid test called Unyvero could help doctors decide sooner whether to stop or change antibiotics in patients on breathing machines with suspected aspiration pneumonia. The trial involved 266 adults in the ICU. The goal was to see if the test reduced th…

This study tested whether having a dietitian help patients with lung disease order meals during a hospital stay could improve their nutrition and reduce the chance of being readmitted after discharge. 41 patients at nutritional risk took part. Researchers measured daily food inta…

This study looked at whether ultrasound can reliably tell if a person's stomach is full before anesthesia, which helps prevent food or liquid from entering the lungs. Twenty-one healthy adults drank different amounts of water, and researchers compared ultrasound accuracy with the…