Articular cartilage disorder

This study compares two surgical methods for repairing large cartilage defects in the knee: augmented microfracture (AMT) and matrix-assisted chondrocyte implantation (MACT). It will enroll 80 people aged 15-50 with symptomatic defects. The goal is to see which technique better i…

This study tests whether taking tranexamic acid pills for a week after knee replacement surgery helps people recover better. 350 adults having their first knee replacement will receive either the drug or a placebo. Researchers will track pain, stiffness, and function for up to 2 …

This study looks at patients who had a cartilage cell transplant (using their own cells on a special material) for knee injuries between 1999 and 2006. Researchers will check their knee function, pain, and quality of life up to 25 years after surgery. The goal is to see how well …

This observational study in Mexico will follow 30 adults already taking tirzepatide for conditions like diabetes or obesity. Researchers will use MRI scans of the knees, CT scans of the heart, and body composition tests to see how the drug affects cartilage, heart fat, and overal…