Articular cartilage disorder

This study looked at the long-term safety and effectiveness of CartiFill, a treatment for knee cartilage damage. Researchers followed 36 people for 6 years after they had microfracture surgery with or without CartiFill. The goal was to see how well the treatment held up over time…

This study tested an experimental protein called LNA043, given as injections into the knee, to see if it can help regrow cartilage in people with knee osteoarthritis or cartilage injuries. 142 adults participated in two parts: one for cartilage lesions and one for osteoarthritis.…

This study tested a treatment called Chondron, which uses a person's own cartilage cells grown in a lab, against a standard surgery called microfracture for knee cartilage damage. 21 adults who had either treatment at least 2 years ago were compared. The goal was to see which app…

This study tested whether adding a collagen device (CartiFill) during microfracture surgery helps heal ankle cartilage defects better than microfracture alone. Sixty patients were enrolled and followed for up to two years. The main goal was to measure pain and satisfaction after …

This Phase 3 trial tested a new one-step treatment called IMPACT for knee cartilage damage. It combines the patient's own cartilage cells with donor stem cells, applied during a single surgery. 60 people aged 18-45 with moderate to severe cartilage lesions were randomly assigned …

This early-phase trial tested a stem cell product called CARTISTEM in 12 adults with knee cartilage defects. The stem cells, derived from human umbilical cord blood, were implanted into the knee to see if they could safely help repair damaged cartilage. The study measured knee fu…

This study tested a special implant called BiCRI in 11 people with knee cartilage damage. The implant is a scaffold that helps new cartilage grow. Researchers measured pain, knee function, and tissue healing. The goal was to see if the implant is safe and works for tough cases, i…