Collagen patch boosts ankle cartilage repair in new trial

NCT ID NCT02519881

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tested whether adding a collagen device (CartiFill) during microfracture surgery helps heal ankle cartilage defects better than microfracture alone. Sixty patients were enrolled and followed for up to two years. The main goal was to measure pain and satisfaction after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

CartiFill (collagen device) used during microfracture surgery

What this could lead to

If it works, this could improve pain and healing for people with ankle cartilage damage, offering a better surgical option.

What could go wrong

This is a small, completed trial with 60 participants. The results may not apply to everyone, and the collagen device may not provide significant benefit over standard microfracture.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

articular cartilage disorder Fractures, Stress

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Eulji general Hospital

    Seoul, Seoul, South Korea

  • Hallym University Medical Center-Kangnam Sacred Heart Hospital

    Seoul, Seoul, South Korea

  • Soon Chun Hyang University Hospital Bucheon

    Bucheon-si, Gyeonggi-do, South Korea