New scaffold implant shows promise for damaged knee cartilage

NCT ID NCT05924763

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a special implant called BiCRI in 11 people with knee cartilage damage. The implant is a scaffold that helps new cartilage grow. Researchers measured pain, knee function, and tissue healing. The goal was to see if the implant is safe and works for tough cases, including failed prior treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Biphasic Cartilage Repair Implant (BiCRI) - a two-phase scaffold made of PLGA and β-TCP

What this could lead to

If successful, this implant could offer a new way to repair knee cartilage damage, potentially reducing pain and improving knee function.

What could go wrong

This was a very small study (11 people) with no comparison group, so results may not apply to everyone. The implant is still experimental and long-term benefits are unknown.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

articular cartilage disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • En Chu Kong Hospital

    New Taipei City, Taiwan

  • Ministry of Health and Welfare Shuang-Ho Hospital

    New Taipei City, Taiwan