New scaffold implant shows promise for damaged knee cartilage
NCT ID NCT05924763
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a special implant called BiCRI in 11 people with knee cartilage damage. The implant is a scaffold that helps new cartilage grow. Researchers measured pain, knee function, and tissue healing. The goal was to see if the implant is safe and works for tough cases, including failed prior treatments.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Biphasic Cartilage Repair Implant (BiCRI) - a two-phase scaffold made of PLGA and β-TCP
- What this could lead to
- If successful, this implant could offer a new way to repair knee cartilage damage, potentially reducing pain and improving knee function.
- What could go wrong
- This was a very small study (11 people) with no comparison group, so results may not apply to everyone. The implant is still experimental and long-term benefits are unknown.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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En Chu Kong Hospital
New Taipei City, Taiwan
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Ministry of Health and Welfare Shuang-Ho Hospital
New Taipei City, Taiwan
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Other studies related to the condition(s) this trial covers.