Aortic aneurysm
MONDO:0005160A ruptured aneurysm located in the wall of the proximal portion of the descending aorta proceeding from the arch of the aorta.
Also known as: abdominal aortic aneurysm, ruptured, aortic aneurysm, aortic aneurysm (disease), aortic aneurysm of unspecified site, ruptured, ruptured abdominal aortic aneurysm, ruptured thoracic aneurysm, ruptured thoracic aortic aneurysm, ruptured thoracoabdominal aortic aneurysm
214 clinical trials for this condition and its sub-types, 104 tagged with Aortic aneurysm itself.
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Sub-types of Aortic aneurysm
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Abdominal aortic aneurysm 114 trials
1 sub-type
- Familial abdominal aortic aneurysm 0 trials · 2 incl. sub-types Sub-types →
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Thoracic aortic aneurysm 76 trials
Most studied deeper sub-types
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Can a new device prevent aortic aneurysm rupture?
Disease control CompletedThis trial is evaluating a new device called the Bifurcated Multilayer Flow Modulator (BMFM) for treating abdominal aortic aneurysms that involve the iliac arteries. The device is designed to be implanted inside the blood vessel to help stabilize the aneurysm and prevent it from …
Sponsor: Cardiatis • Aim: Disease control
Last updated Sep 05, 2026 00:00 UTC
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Can a 5-Minute clamp before surgery save lives?
Disease control CompletedThis study tested whether briefly stopping blood flow to the aorta before surgery (called ischemic pre-conditioning) could reduce complications in people undergoing open repair of a thoracoabdominal aortic aneurysm. 65 patients were randomly assigned to receive either the pre-con…
Sponsor: University Hospital, Rouen • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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New anchor device aims to secure aortic aneurysm repairs
Disease control CompletedThis registry tracked over 1,000 patients who received the Heli-FX EndoAnchor device during endovascular repair of aortic aneurysms. The device is designed to help hold the endograft in place and prevent leaks. Patients were followed for up to 5 years to see how safe and effectiv…
Sponsor: Medtronic Cardiovascular • Aim: Disease control
Last updated Jun 27, 2026 12:08 UTC
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Tailored stents show promise for Hard-to-Treat aneurysms
Disease control CompletedThis study looked at 47 people with thoracoabdominal aortic aneurysms (a bulge in the main artery in the chest and belly). They received a custom-made stent graft (a fabric-covered metal tube) designed to fit their unique anatomy. The goal was to see if the aneurysm size stayed s…
Sponsor: JOTEC GmbH • Aim: Disease control
Last updated Jun 27, 2026 09:05 UTC
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Ketamine may cut opioid use after major aortic surgery
Symptom relief CompletedThis study is testing whether a low dose of ketamine can reduce the amount of strong painkillers (opioids) needed and improve pain control in people recovering from thoracic endovascular aortic repair (TEVAR). About 30 adults scheduled for this surgery will receive either ketamin…
Phase 2 • Sponsor: Eric Johnson • Aim: Symptom relief
Last updated Sep 21, 2026 22:00 UTC
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AI may spot dangerous aortic growth before it happens
Knowledge-focused CompletedThis study is testing whether an artificial intelligence model can predict how the aorta might dilate (widen) in people with bicuspid aortic valve—a common heart valve condition that raises the risk of aortic aneurysm. Researchers will analyze CT scans from 1,000 patients who had…
Sponsor: Second Affiliated Hospital, Zhejiang University, School of Medicine • Aim: Knowledge-focused
Last updated Aug 26, 2026 00:00 UTC
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Can a Stick-On AI patch replace wires for heart monitoring after surgery?
Knowledge-focused CompletedThis study tests a small, wearable ECG patch that uses artificial intelligence to monitor heart rhythms in patients recovering from cardiac surgery. Participants wear the patch for up to a week after leaving the intensive care unit. The goal is to see if the device can reliably t…
Sponsor: HUINNO Co., Ltd • Aim: Knowledge-focused
Last updated Aug 01, 2026 00:00 UTC
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Mesh fails to prevent hernias in aortic repair patients
Knowledge-focused CompletedThis study looked at whether placing a mesh during abdominal aortic aneurysm repair could prevent incisional hernias later. Fifty patients were split into two groups: one got mesh reinforcement, the other standard closure. After follow-up, the mesh did not show a clear benefit in…
Sponsor: Hospital Universitario Ramon y Cajal • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC
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Aging proteins in artery walls could be key to aneurysm mystery
Knowledge-focused CompletedThis study looked at whether natural aging of proteins in blood vessel walls contributes to the development of aortic aneurysms. Researchers measured skin autofluorescence and collected blood and skin samples from 24 patients undergoing surgery for abdominal aortic aneurysms. The…
Sponsor: CHU de Reims • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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New monitoring methods aim to prevent paralysis after aortic surgery
Knowledge-focused CompletedThis study tests two new monitoring techniques—long loop reflexes (F-waves) and near-infrared spectroscopy (NIRS)—to detect spinal cord ischemia early after thoracoabdominal aortic aneurysm repair. Current methods work during surgery but are too painful for awake patients afterwa…
Sponsor: Maastricht University Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC