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Anti-HLA hyperimmunization

MONDO:0016351

Anti-HLA hyperimmunization is an increase in anti-HLA antigens mostly seen in chronic renal failure (CRF) patients that have undergone hemodialysis and polytransfusion.

3 clinical trials for this condition and its sub-types.

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Broader categories

Disease (717) Immune system disorder (150) Human disease (15) Disease by body system or component (0)

Trials to join now! 1 Not yet recruiting 1 Terminated 1

Stem cell reset could open door to kidney transplants for 'Impossible' patients

Disease control Recruiting now

This early-phase trial tests whether a powerful immune reset using a patient's own stem cells can clear the antibodies that block them from receiving a kidney transplant. Ten highly sensitized adults with end-stage kidney disease will undergo intense conditioning to wipe out thei…

Phase 1/2 • Sponsor: Hospital Universitari Vall d'Hebron Research Institute • Aim: Disease control

Last updated Jun 27, 2026 13:03 UTC