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Anti-HLA hyperimmunization

MONDO:0016351

Anti-HLA hyperimmunization is an increase in anti-HLA antigens mostly seen in chronic renal failure (CRF) patients that have undergone hemodialysis and polytransfusion.

9 clinical trials for this condition and its sub-types.

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Broader categories

Disease (618) Immune system disorder (140) Human disease (14) Disease by body system or component (0)

Trials to join now! 6 Completed 2 Terminated 1

New hope for kidney patients with Hard-to-Match immune systems

Disease control Terminated

This study tested two drugs, daratumumab and belatacept, in 5 highly sensitized dialysis patients waiting for a kidney transplant. The goal was to safely reduce the antibodies that make it very hard to find a compatible donor kidney. The trial was stopped early, but it aimed to h…

Phase: PHASE2 • Sponsor: University Hospital, Grenoble • Aim: Disease control

Last updated Jun 27, 2026 08:03 UTC