Anismus
MONDO:0000480A focal dystonia of the pelvic floor muscles during attempted defecation.
Also known as: anal region skeletal muscle focal dystonia, focal dystonia of anal region skeletal muscle, dyskinetic puborectalis, dyssynergic defecation, puborectalis syndrome, rectosphincteric dyssynergia, spastic pelvic floor syndrome, sphincteric disobedience syndrome
56 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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Keyhole surgery aims to fix multiple pelvic organ prolapses at once
Disease control CompletedThis study tested a new keyhole surgery (laparoscopic vaginorectopexy) in 25 women with multiple pelvic organ prolapses causing bowel problems. Researchers checked how well the surgery worked by looking at prolapse recurrence, bowel function, and quality of life up to 12 months a…
Phase: NA • Sponsor: Sahlgrenska University Hospital • Aim: Disease control
Last updated Jun 27, 2026 08:00 UTC
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New scale could help predict fall risk for hospital patients in turkey
Diagnosis CompletedThis study tested a Turkish version of the Johns Hopkins In-Room Independence Scale, which measures a patient's ability to move, use the toilet, and think clearly while in their hospital room. Researchers worked with 100 adults who had conditions like stroke, Parkinson's, or ampu…
Sponsor: Sisli Hamidiye Etfal Training and Research Hospital • Aim: Diagnosis
Last updated Jun 27, 2026 09:08 UTC
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New balloon device could spot hidden cause of constipation
Diagnosis CompletedThis study tested whether a new device called EndoFLIP can better diagnose anismus, a condition where the anal muscles don't relax properly during bowel movements, causing severe constipation. Researchers measured anal stretchiness in 61 patients with chronic constipation and com…
Phase: NA • Sponsor: University Hospital, Rouen • Aim: Diagnosis
Last updated Jun 26, 2026 15:40 UTC
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Shocking constipation away: nerve zap trial for kids
Symptom relief CompletedThis completed trial tested whether a nerve stimulation treatment called PTNS can help children aged 8-18 with constipation caused by pelvic floor dyssynergia. Forty participants received either real PTNS or a sham (fake) treatment to see if it improves bowel function. The goal i…
Phase: NA • Sponsor: Nationwide Children's Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 09:11 UTC
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Physiotherapy students test muscle relief techniques on themselves
Symptom relief CompletedThis study looked at how common muscle and posture problems are in physiotherapy students and whether a special physiotherapy program could help. 44 students with back pain and muscle tightness received treatments like trigger point release, stretching, and joint mobilization. Th…
Phase: NA • Sponsor: Charles University, Czech Republic • Aim: Symptom relief
Last updated Jun 27, 2026 08:13 UTC
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Who should control your sedation during surgery? new study compares options
Symptom relief CompletedThis study looked at whether letting patients control their own sedation during arm surgery under regional anesthesia leads to higher satisfaction compared to having an anesthesiologist control it. 70 adults having upper limb orthopedic surgery were randomly assigned to either pa…
Phase: NA • Sponsor: GCS Ramsay Santé pour l'Enseignement et la Recherche • Aim: Symptom relief
Last updated Jun 27, 2026 07:59 UTC
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Brain study sheds light on Parkinson's and tics
Knowledge-focused CompletedThis completed study from the National Institute of Neurological Disorders and Stroke aimed to better understand how the brain controls movement and what goes wrong in movement disorders like Parkinson's disease, Tourette's syndrome, and dystonia. Over 1,200 adults—both patients …
Phase: NA • Sponsor: National Institute of Neurological Disorders and Stroke (NINDS) • Aim: Knowledge-focused
Last updated Jul 04, 2026 00:00 UTC
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Study probes hidden mental toll of chronic constipation disorder
Knowledge-focused CompletedThis study looks at whether people with dyssynergic defecation—a condition where the pelvic muscles don't relax properly during bowel movements—are more likely to have psychiatric disorders like anxiety or depression. Researchers will compare 148 patients to healthy volunteers us…
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Jul 03, 2026 00:00 UTC
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New turkish health survey could improve care for muscle and joint problems
Knowledge-focused CompletedThis study translated the Generic Functional Index, a questionnaire that measures how well people can do daily activities, into Turkish. Researchers tested it with 200 adults who have muscle or joint problems to see if it is accurate and reliable. The goal is to give Turkish-spea…
Sponsor: Istanbul Bilgi University • Aim: Knowledge-focused
Last updated Jun 28, 2026 00:00 UTC
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Weight may weaken nerve therapy for stubborn constipation
Knowledge-focused CompletedThis completed study looked at 60 people with obstructed defecation, a severe form of constipation. Researchers compared how well a noninvasive nerve stimulation treatment worked in obese versus non-obese participants. The goal was to see if body weight changes the treatment's ab…
Phase: NA • Sponsor: General Committee of Teaching Hospitals and Institutes, Egypt • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:25 UTC
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Dystonia study reveals hidden brain changes beyond muscle twists
Knowledge-focused CompletedThis study looked at 102 adults with dystonia, a condition causing involuntary muscle contractions. Researchers used questionnaires and brain wave recordings to assess memory, attention, mood, and decision-making. The goal was to better understand the non-motor symptoms of dyston…
Phase: NA • Sponsor: IRCCS Centro Neurolesi Bonino Pulejo • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:02 UTC
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Physios take on ER duty: study tests if they can replace doctors for back pain
Knowledge-focused CompletedThis study tested whether specially trained physiotherapists can safely diagnose and treat non-urgent muscle and joint pain in the emergency room, compared to standard care from doctors. 102 patients with back, neck, or shoulder pain were randomly assigned to either a physiothera…
Phase: NA • Sponsor: Bern University of Applied Sciences • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Can CRPS patients imagine movement? new study investigates
Knowledge-focused CompletedThis completed study compared how well people with complex regional pain syndrome (CRPS), people with other muscle or bone pain, and healthy individuals can imagine movements. Researchers used a questionnaire called the MIQ-RS to measure motor imagery skills. The goal was to see …
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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Wrist-Worn gadget could help doctors monitor Parkinson's at home
Knowledge-focused CompletedThis study tested a wrist-worn device called the Personal KinetiGraph (PKG) to see if it can accurately measure movement problems in people with Parkinson's disease. Nineteen participants wore the device while researchers compared its readings to standard clinical tests and video…
Sponsor: Global Kinetics Corporation • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC
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Mind, spirit, and pain: new study explores what chronic pain patients really believe
Knowledge-focused CompletedThis study surveyed 116 adults with chronic pain at a rehabilitation clinic to understand how their pain beliefs, spiritual well-being, and attitudes toward complementary and alternative medicine are related. Participants filled out several questionnaires about their pain, mood, …
Sponsor: Gulseren Demir Karakilic • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC