Angle-closure glaucoma
MONDO:0001744The sudden increase of intraocular pressure, resulting in pain and an abrupt decrease in visual acuity.
Also known as: angle closure glaucoma
27 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsSub-types
Broader categories
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Eylea eyed as treatment for glaucoma caused by abnormal blood vessels
Disease control Recruiting nowThis study is tracking 480 people with neovascular glaucoma, a serious eye condition, who are receiving the drug Eylea (aflibercept) as part of their normal care. Researchers are monitoring side effects and how well the drug controls eye pressure and vision over 6 months. The goa…
Sponsor: Bayer • Aim: Disease control
Last updated Jul 02, 2026 00:00 UTC
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New combo surgery may better control glaucoma pressure
Disease control Recruiting nowThis study tests whether adding an extra step (a special blade to open drainage channels) to standard cataract-and-glaucoma surgery can better lower eye pressure in people with chronic angle-closure glaucoma and cataracts. About 68 adults will be randomly assigned to one of two s…
Phase: NA • Sponsor: Peking University People's Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:05 UTC
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Glaucoma patients: could this supplement save your sight?
Disease control Recruiting nowThis study tests whether a daily supplement called BrudyGlauco (containing DHA and citicoline) can help protect eyesight in people with glaucoma. About 108 participants will take either the supplement or a placebo for 12 months. The goal is to see if it slows vision loss and impr…
Phase: NA • Sponsor: Institut Catala de Retina • Aim: Disease control
Last updated Jun 27, 2026 08:11 UTC
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Glaucoma surgery showdown: new procedure may offer safer option
Disease control Recruiting nowThis study compares two surgical procedures for people with primary angle-closure glaucoma: Phaco-GSL (cataract surgery combined with a procedure to open the eye's drainage angle) and trabeculectomy (a standard glaucoma surgery that creates a new drainage pathway). Researchers wa…
Phase: NA • Sponsor: University of Medicine and Pharmacy at Ho Chi Minh City • Aim: Disease control
Last updated Jun 26, 2026 15:37 UTC
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Eye scan may spot hidden blood-flow changes that signal glaucoma risk in diabetes
Knowledge-focused Recruiting nowThis observational study uses a painless, non-invasive eye scan called iris OCTA to measure blood flow in the iris of people with type 2 diabetes. Researchers want to see if blood-flow patterns differ between healthy eyes, diabetic eyes without complications, and those with diabe…
Sponsor: Qilu Hospital of Shandong University • Aim: Knowledge-focused
Last updated Jul 30, 2026 00:00 UTC
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New eye scans may unlock secrets of glaucoma blindness
Knowledge-focused Recruiting nowThis study will use advanced eye scans (OCT and OCTA) to compare the structure and blood flow of the choroid and retina in people with two main types of glaucoma: primary angle-closure disease and primary open-angle glaucoma. Researchers aim to better understand how these conditi…
Sponsor: Zhongshan Ophthalmic Center, Sun Yat-sen University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:32 UTC
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Scientists probe molecular secrets of glaucoma eye strain
Knowledge-focused Recruiting nowThis study looks at why some people with primary angle-closure glaucoma have loose eye lenses (zonular laxity). Researchers will compare molecules from 150 participants—those with and without this lens looseness, plus healthy controls—to find key differences. The goal is to bette…
Sponsor: Zhongnan Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:10 UTC
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New eye imaging study could unlock secrets of glaucoma
Knowledge-focused Recruiting nowThis study looks at how tiny fibers in the eye, called the vitreous zonule, might play a role in causing primary angle-closure glaucoma, a serious eye condition. Researchers will use advanced 3D ultrasound to take detailed pictures of these fibers in 440 adults, including those w…
Sponsor: Peking University People's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:06 UTC
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Glaucoma surgery study asks patients: how do you really feel?
Knowledge-focused Recruiting nowThis study follows 132 adults having glaucoma surgery to see how their quality of life changes over six months. Patients fill out a questionnaire about vision-related daily activities before and after surgery. The goal is to compare different surgical techniques from the patient'…
Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC
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Inside the eye: new imaging study tracks healing after glaucoma surgery
Knowledge-focused Recruiting nowThis study uses special cameras to watch how eye tissues heal after minimally invasive glaucoma surgery. Researchers will follow 300 glaucoma patients to measure changes in the eye's drainage angle over time. The goal is to learn more about healing patterns and help improve futur…
Sponsor: Zhongshan Ophthalmic Center, Sun Yat-sen University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC