Glaucoma surgery showdown: new procedure may offer safer option

NCT ID NCT06952153

First seen Jun 26, 2026 ยท Last updated Jun 26, 2026

Summary

This study compares two surgical procedures for people with primary angle-closure glaucoma: Phaco-GSL (cataract surgery combined with a procedure to open the eye's drainage angle) and trabeculectomy (a standard glaucoma surgery that creates a new drainage pathway). Researchers want to see which one controls eye pressure better and has fewer side effects. About 82 participants will be randomly assigned to one of the two surgeries and followed for a year.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Phacoemulsification with Goniosynechialysis (Phaco-GSL) and Trabeculectomy with 5FU
What this could lead to
If this trial succeeds, it could show that Phaco-GSL is a safer or equally effective alternative to trabeculectomy for controlling eye pressure in glaucoma patients.
What could go wrong
This is a small, early-stage trial with only 82 participants, so results may not apply to all patients. Both surgeries carry risks like infection, bleeding, or vision changes.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • HCMC University of Medicine and Pharmacy

    RECRUITING

    Ho Chi Minh City, Vietnam

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