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Adrenomyeloneuropathy

MONDO:0015339

An adult form of the peroxisomal disease X-linked adrenoleukodystrophy (X-ALD), characterized by spastic paraparesia and often associated with peripheral adrenal insufficiency in males. Both males and females can be affected with AMN.

Also known as: AMN, adrenomyeloneuropathy

16 clinical trials for this condition and its sub-types.

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Broader categories

Dementia (698) Disease (680) Psychiatric disorder (435) Cognitive disorder (433) Metabolic disease (233) Nervous system disorder (231) Hereditary disease (176) Neurodegenerative disease (171) Peripheral nervous system disorder (114) Central nervous system disorder (107)

Trials to join now! 8 Not yet recruiting 1 Not yet finished but already full! 1 Completed 3 Terminated 3

Can a common MS drug help people with a rare nerve disease walk better?

Disease control Ongoing

This clinical trial is testing whether dimethyl fumarate, a drug already used for multiple sclerosis, can improve balance and walking in adults with adrenomyeloneuropathy (AMN), a rare nerve disease. Forty participants will take either the drug or a placebo daily for 36 months, w…

Phase: PHASE2, PHASE3 • Sponsor: Pujol, Aurora, M.D. • Aim: Disease control

Last updated Jun 27, 2026 14:00 UTC