Acromegaly
MONDO:0019933Acromegaly is an acquired disorder related to excessive production of growth hormone (GH) and characterized by progressive somatic disfigurement (mainly involving the face and extremities) and systemic manifestations.
Also known as: Growth hormone excess, pituitary giant, somatotroph adenoma
33 clinical trials for this condition and its sub-types.
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New monthly injection aims to tame acromegaly safely
Disease control CompletedThis study tested a monthly injection called CAM2029 (octreotide) in 135 adults with acromegaly, a condition where the body makes too much growth hormone. The goal was to see if the drug is safe and keeps hormone levels under control over 12 months. Participants had already been …
Phase: PHASE3 • Sponsor: Camurus AB • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC
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New hope for kids with gigantism: daily shot may tame growth hormone
Disease control CompletedThis study tested a drug called pegvisomant in children aged 2 to 18 with gigantism, a condition where the body makes too much growth hormone. The goal was to see if the drug could safely lower hormone levels and slow down abnormal growth. Participants received daily injections a…
Phase: PHASE3 • Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) • Aim: Disease control
Last updated Jun 27, 2026 07:56 UTC
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Can a ketogenic diet tame acromegaly hormones?
Disease control CompletedThis study tested whether a three-week ketogenic diet could improve hormone and metabolic measures in 26 adults with active acromegaly, compared to a Mediterranean diet. Participants followed each diet for three weeks, with a two-week break in between. The main goal was to see ch…
Phase: NA • Sponsor: University of Palermo • Aim: Disease control
Last updated Jun 26, 2026 14:16 UTC
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Can a simple sugar test spot acromegaly better?
Diagnosis CompletedThis study looked at whether a standard glucose tolerance test (drinking a sugary solution) can reliably diagnose acromegaly, a condition caused by too much growth hormone. Researchers tested 109 people, some with acromegaly and some without, giving them two glucose tests and one…
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Diagnosis
Last updated Jun 27, 2026 08:00 UTC
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New software could improve acromegaly care
Knowledge-focused CompletedThis study tested a new software tool called ACRODAT that helps doctors track disease activity in people with acromegaly. The tool looks at five key factors like hormone levels, symptoms, and quality of life. Researchers compared patients whose doctors used ACRODAT to those recei…
Sponsor: University of Aarhus • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:07 UTC
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Researchers measure breathing, strength, and quality of life in hospitalized endocrine patients
Knowledge-focused CompletedThis completed observational study at Uşak University examined 150 adults hospitalized in the endocrinology department. Researchers measured breathing, muscle strength, pain, fatigue, sleep quality, physical activity, balance, and nerve function. The goal was to better understand…
Sponsor: Uşak University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
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Can a simple test right after surgery predict acromegaly cure?
Knowledge-focused CompletedThis study followed 20 adults with acromegaly for one year after pituitary surgery. Researchers measured growth hormone and related substances at several time points to see if early test results could predict whether the disease goes into remission. The goal is to find better way…
Sponsor: Cedars-Sinai Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC