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Can a ketogenic diet tame acromegaly hormones?

NCT ID NCT07100587

Completed Disease control Sponsor: University of Palermo Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested whether a three-week ketogenic diet could improve hormone and metabolic measures in 26 adults with active acromegaly, compared to a Mediterranean diet. Participants followed each diet for three weeks, with a two-week break in between. The main goal was to see changes in IGF-1 levels, along with weight, blood sugar, and inflammation markers.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
ketogenic diet and Mediterranean diet
What this could lead to
If successful, this could show that a short-term ketogenic diet helps control hormone levels and improve metabolic health in people with acromegaly.
What could go wrong
This is a small, early-stage study with only 26 participants and short diet periods. Results may not apply to all patients, and the ketogenic diet can be hard to follow long-term.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

acromegaly

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACROMEGALY

Contacts and locations

Locations

  • Policlinico Paolo Giaccone

    Palermo, Italy

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