New hope for kids with gigantism: daily shot may tame growth hormone

NCT ID NCT03882034

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a drug called pegvisomant in children aged 2 to 18 with gigantism, a condition where the body makes too much growth hormone. The goal was to see if the drug could safely lower hormone levels and slow down abnormal growth. Participants received daily injections at home for 60 weeks, with regular check-ups and blood tests. The study aimed to find a treatment option for children who haven't responded to other therapies.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States