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46 XX gonadal dysgenesis
MONDO:000929946,XX gonadal dysgenesis (46,XX GD) is a primary ovarian defect leading to premature ovarian failure (POF) in otherwise normal 46,XX females as a result of failure of the gonads to develop or due to resistance to gonadotrophin stimulation.
Also known as: 46,XX complete gonadal dysgenesis, 46,XX gonadal dysgenesis, 46,XX ovarian dysgenesis, 46,XX pure gonadal dysgenesis, FSH-RO, XX female gonadal dysgenesis, XX-GD, follicular stimulating hormone-resistant ovaries
76 clinical trials for this condition and its sub-types.
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New sperm-sorting chip could boost IVF success rates
Disease control OngoingThis study compares a new microfluidic device, SwimCount Harvester, to standard sperm preparation methods in couples undergoing IVF with genetic testing (PGT-A). About 1,600 couples will be randomly assigned to one of the two methods. The goal is to see if the device leads to mor…
Phase: NA • Sponsor: MotilityCount aps • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC
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Fertility breakthrough? new additive may boost IVF success
Symptom relief OngoingThis study tests whether adding a substance called cpFT to the liquid used to grow eggs and embryos can increase the number of live births in women under 37 who are having a type of IVF called ICSI. About 366 couples took part. The goal is to see if this simple change can improve…
Phase: PHASE3 • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Symptom relief
Last updated Jun 27, 2026 08:00 UTC
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AI watches embryo movies to predict IVF success
Knowledge-focused ENROLLING_BY_INVITATIONThis study records 30-second videos of embryos from 1,000 IVF patients and uses artificial intelligence to analyze their movement patterns. The goal is to see if these patterns can predict whether an embryo will lead to a successful pregnancy. Participants receive standard care a…
Sponsor: Viable Biosciences • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:39 UTC
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Resident's journey to master scarless hysterectomy under the microscope
Knowledge-focused OngoingThis study watches a single gynecology resident as they learn to perform a hysterectomy through the vagina using a special camera, leaving no belly scars. The goal is to see how quickly the resident improves, measuring surgery time and any complications. Nineteen women with benig…
Sponsor: Cukurova University • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC
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New biobank aims to unlock secrets of infertility and pregnancy
Knowledge-focused ENROLLING_BY_INVITATIONThis study is creating a biobank—a collection of blood samples and health data—to help researchers better understand gynecological disorders, infertility in men and women, and pregnancy-related conditions. Up to 3,000 participants will provide samples at San Raffaele Hospital in …
Sponsor: IRCCS San Raffaele • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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Brain scans reveal hidden links between body diseases and metabolism
Knowledge-focused OngoingThis study watches 200 people with lung, gut, or hormone diseases over time using special brain scans (PET). It aims to see how these diseases change brain activity and whether those changes can predict tumor return, spread, or survival. No new treatment is tested—just observatio…
Sponsor: The First Affiliated Hospital of Zhengzhou University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC