46 XX gonadal dysgenesis
MONDO:000929946,XX gonadal dysgenesis (46,XX GD) is a primary ovarian defect leading to premature ovarian failure (POF) in otherwise normal 46,XX females as a result of failure of the gonads to develop or due to resistance to gonadotrophin stimulation.
Also known as: 46,XX complete gonadal dysgenesis, 46,XX gonadal dysgenesis, 46,XX ovarian dysgenesis, 46,XX pure gonadal dysgenesis, FSH-RO, XX female gonadal dysgenesis, XX-GD, follicular stimulating hormone-resistant ovaries
5 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsSub-types
Broader categories
-
Frozen ovary tissue awakened to restore fertility in women with early menopause
Disease control CompletedThis study tested a new technique to help women with primary ovarian insufficiency (early ovarian failure) become pregnant. Doctors removed one ovary, treated small pieces of it with drugs to wake up dormant eggs, and then transplanted the tissue back into the patient. After moni…
Sponsor: The First Affiliated Hospital of Zhengzhou University • Aim: Disease control
Last updated Jun 27, 2026 12:38 UTC
-
Fertility boost? study tests estradiol and guaifenesin alongside clomiphene
Disease control CompletedThis study looked at whether adding vaginal estradiol or oral guaifenesin to standard fertility treatment (clomiphene citrate) could improve pregnancy rates. 90 women with infertility were randomly assigned to one of three groups. The goal was to see if these add-ons helped with …
Phase: NA • Sponsor: Yuzuncu Yil University • Aim: Disease control
Last updated Jun 27, 2026 09:03 UTC
-
Can a simple uterine flush boost IVF pregnancy rates?
Knowledge-focused CompletedThis study looked at whether flushing the uterus with a low dose of the hormone hCG right after egg retrieval could improve pregnancy rates in women undergoing IVF. Researchers measured immune markers and blood flow in the uterus to see if the flush made the womb more receptive t…
Phase: PHASE4 • Sponsor: Omayma Ismail Khalaf • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:57 UTC