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127005 trials found · Page 6233 of 6351
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Healthy volunteers needed to test safety of experimental drug budoprutug
Knowledge-focused CompletedThe main objective is to assess the safety and tolerability of subcutaneous and intravenous injection forms of budoprutug in healthy volunteers.
Early phase 1 • Sponsor: Climb Bio, Inc. • Aim: Knowledge-focused
Last updated Aug 01, 2026 00:00 UTC
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Throat cancer radiation trial targets saliva ducts to stop dry mouth
Symptom relief CancelledRadiation-induced xerostomia (dry mouth) is one of the most common and severe toxicities experienced by patients undergoing radiation treatment for head and neck cancer. Radiation-induced dry mouth is a frequently experienced symptom and persists after treatment, potentially inde…
Sponsor: UNC Lineberger Comprehensive Cancer Center • Aim: Symptom relief
Last updated Jun 26, 2026 13:32 UTC
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Meal timing matters: new drug tested with and without food
Knowledge-focused CompletedThis is a Phase 1, open-label, randomized, three-period crossover trial study to evaluate the effect of food and dosing and meal timing intervals on the pharmacokinetics (PK) of HSK46575 in healthy adult participants ,with an exploratory assessment of excretion pathways and excre…
Phase 1 • Sponsor: Haisco Pharmaceutical Group Co., Ltd. • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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New study checks if etrasimod passes into breast milk
Knowledge-focused Recruiting nowThis study aims to figure out how much etrasimod, a medication, ends up in breast milk after taking it for several days. To do this, the researchers will work with at least 8 healthy women who are breastfeeding. These women will take a 2 mg dose of etrasimod every day for 7 days …
Phase 1 • Sponsor: Pfizer • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC
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Bilingual brain study seeks 360 volunteers
Knowledge-focused Recruiting nowThis study aims to investigate how unimodal bilinguals who speak two languages and bimodal bilinguals who speak one language and sign another control languages across comprehension and production. Participants will complete different language tasks (e.g., classify a word, name a …
Sponsor: University of California, San Diego • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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Sticky heart patch put to the test in healthy volunteers
Knowledge-focused CompletedThis study will be a single center, single arm, open-label, prospective study to evaluate adhesive performance of the Bardy Diagnostics' (BardyDx) MCT Patch up to 30 days of wear.
Sponsor: Baxter Healthcare Corporation • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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Meal timing tested for new drug TS-172 in healthy volunteers
Knowledge-focused CompletedAn open-label, single-center, crossover study to evaluate the impact of administration timing of TS-172 on the pharmacodynamics in healthy adult male subjects.
Phase 1 • Sponsor: Taisho Pharmaceutical Co., Ltd. • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC
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Seed-Packed lunch: a simple trick to curb hunger?
Knowledge-focused OngoingThe goal of the study is to determine the likability of seeds incorporated into lunch foods. The study will provide a better understanding of ways to make recipe alterations that may promote health and fullness.
Sponsor: USDA Beltsville Human Nutrition Research Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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New drug AN2-502998 tested in healthy people for first time
Knowledge-focused CompletedFirst-in-Human Phase 1, Single-Center, Randomized, Blinded, Placebo-Controlled Trial in Healthy Adults to Evaluate the Safety, Tolerability, and Pharmacokinetics of Single and Multiple Doses of Oral AN2-502998
Phase 1 • Sponsor: AN2 Therapeutics, Inc • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:25 UTC
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Healthy men needed to track mystery Drug's path through the body
Knowledge-focused Stopped earlyThis trial is intended to investigate the mass balance, metabolism, and basic pharmacokinetics of BI 1819479 (C-14) (Part A) and to investigate the absolute bioavailability of BI 1819479 (Part B) in healthy male volunteers.
Phase 1 • Sponsor: Boehringer Ingelheim • Aim: Knowledge-focused
Last updated Aug 23, 2026 00:00 UTC
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Promising prostate cancer trial pulled before it began
Disease control CancelledThe purpose of the study is to examine the clinical and biological effects of 177Lu-PSMA-617 in mCRPC patients with cytopenia\[s\].
Phase 2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 12:30 UTC
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Pregnancy and paychecks: new training aims to protect working moms
Knowledge-focused CancelledResearch Aim 1: Determine the effectiveness of PROMOTE vs. usual care to increase patients' receipt of counseling about workplace accommodations and pregnancy. We will recruit and randomize Obstetric providers to the PROMOTE intervention or usual care. The investigators will comp…
Sponsor: Duke University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC
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Knee study withdrawn before it even started
Knowledge-focused CancelledThis study will investigate whether knee joint manipulation can improve neurocognitive and neuromuscular performance in individuals with a history of anterior cruciate ligament reconstruction (ACLR). Recruitment will consist of 30 participants aged 18-35 who are 4 months to 5 yea…
Sponsor: University of North Carolina, Chapel Hill • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Bone cement study for revision joint surgery withdrawn before start
Knowledge-focused CancelledThe goal of this post-market study is to confirm the safety, performance and clinical benefits of the Refobacin Revision-3 Bone Cement when used in knee or hip revision surgeries. This will be done by collecting information on: * removal of any metal components of the hip or kne…
Sponsor: Zimmer Biomet • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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Pork for brain power? study pulled before it began
Knowledge-focused CancelledThe goal of this clinical trial is to learn if eating more lean pork will lead to better cognition and a healthier brain in older adults. The main questions it aims to answer are: * Does eating more lean pork lead to higher scores on cognitive tests and better quality of life? *…
Sponsor: University of Nebraska Lincoln • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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New tool measures hidden burden on parents of kids with drug allergies
Knowledge-focused CompletedThis study aims to evaluate the psychometric properties of the Turkish version of the Parent-reported Drug Hypersensitivity Quality of Life Questionnaire (P-DrHy-Q), a disease-specific instrument assessing the health-related quality of life (HRQoL) in caregivers of children with …
Sponsor: Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:02 UTC
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Real-world study of advanced breast cancer treatments withdrawn before starting
Knowledge-focused CancelledThe goal of this observational study is to learn about the safety and effectiveness of people with advanced breast cancer that is hormone receptor-positive (HR+), HER2-negative (HER2-). Participants will: Allow researchers to collect medical data during routine care Be followe…
Sponsor: SciClone Pharmaceuticals • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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Nutrition lessons boost healthy habits in nursing students
Knowledge-focused CompletedThis study aims to evaluate the effects of a structured nutrition education program on nursing students' nutrition knowledge, dietary behaviors, physical activity levels, and sleep quality. University students, particularly those studying in health-related fields, often experienc…
Sponsor: Agri Ibrahim Cecen University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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Where should you get cataract surgery? study compares costs
Knowledge-focused CompletedTo analyze the economics of office-based (OBS) versus ambulatory surgery center (ASC)-based cataract surgery.
Sponsor: Rush Eye Associates • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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Zapped to attention: ultrasound brain boost trial pulled before start
Knowledge-focused CancelledThe investigators goal is to target FUS energy to the centromedian nucleus of the thalamus (CMT), the core of arousal, which is inaccessible by traditional non-invasive neuromodulation devices. The CMT is an ideal stimulation target for augmenting alertness, as it is intimately l…
Early phase 1 • Sponsor: Medical University of South Carolina • Aim: Knowledge-focused
Last updated Jun 26, 2026 14:23 UTC