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The purpose of this study is to see how a medicine called PF-08049820 affects how other medicines move through the body. This information will help plan future studies. The other medicines include: * Birth control pills (containing ethinyl estradiol and levonorgestrel) * Midazol…

Drug: 2 single oral doses of midazolam, 2 single oral doses of prednisolone , and clofutriben once daily for 16 days.

The purpose of this exploratory study is to assess the adhesive forces to skin of samples over the period of 24 hours to establish the peel-off measurement method at the Essity study site.

The purpose of this study is to collect information for scientific research and to better understand awareness and to understand overall risk awareness, diagnoses and treatment related to liver related diseases. The study aims to collect valid responses through online questionnai…

The purpose of this post-market clinical follow-up (PMCF) study is to evaluate the long-term safety and performance of 3 commercially available contact lens cleaning and disinfecting solutions in a pediatric population. This study will be conducted in Canada and the US.

Acute renal failure after cardiac surgery is a common postoperative complication, affecting approximately 20% of patients. It is associated with an increase in short-term mortality and an increase in hospital stay; but is also associated with an increase in long-term mortality of…

The goal of this clinical trial is to learn if Brief Dialectical Behavior Therapy Skills Training (DBT-BST) can prevent suicidality in adults. The main questions it aims to answer are: * Does DBT-BST provide coping strategies (e.g., emotion regulation) to participants with suici…

The purpose of the current investigation is to provide proof of concept for a future approach to improve UF prediction accuracy. While building on the ideas of the past, the concept is augmented by leveraging additional diagnostic technologies and digital data analytics methodolo…

This study aims to better understand the potential side effects of a heart treatment called PFA (Pulsed Field Ablation), used to treat an arrhythmia known as atrial fibrillation. This technique has already been in clinical use for several years. The goal of the study is to detec…

This project is being completed to test the usability and safety of the Watch-Transcutaneous Electrical Acustimulation (TEA) Device. This is a pilot study that will lead to future projects for cancer patients that may experience chemotherapy-induced symptoms.

The purpose of this study is to assess the effectiveness of a novel mHealth intervention that is being designed to promote self-efficacy and response willingness among Pakistan-based emergency department health care workers (HCWs) in public health emergencies and disasters. This …

The goal of this observational study is to assess and describe the epidemiology of traumatic hand injuries in Sohag University Hospital in different age group ,male, female with traumatic hand injury The main questions it aims to answer are: what is the mechanism of injury ? wha…

Age, body mass index, and modern technological influences predisposed to high prevalence of postural deviations such as forward head posture and thoracic hyperkyphosis, and rounded shoulders among school-aged children. The comprehensive integration of developmental and biomechani…

This study is to assess the prevalence of different incisal angle of maxillary central incisors in a sample of adults.Materials and methods: The current study will include 500 sound natural maxillary central incisors in 350 Participants. intraoral scan will be taken for all cases…

The purpose of this study is to evaluate a new strategy to treat small breast cancer called cryoablation, or cryosurgery, in combination with biopsy methods which are guided by certain imaging like mammography.

The goal of this clinical trial is to understand how environmental factors influence comfort and health. The main question it aims to answer is: * do temperature, visuals, and sounds affect a person's physiology and perception? Participants will watch short videos in 2 differen…

This randomized controlled trial aims to evaluate the effects of art education on imagination, individual creativity, and state mindfulness levels in midwifery students. The study will be conducted among third-year midwifery students at the Faculty of Health Sciences, Selçuk Univ…

The purpose of this post-market clinical follow-up (PMCF) study is to evaluate the long-term safety and performance of 2 commercially available contact lens cleaning and disinfecting systems in a pediatric population.

The goal of this observational study is to learn about blood pressure response to the vasopressor drug vasopressin in people with septic shock. The main questions it aims to answer are: * Are the levels of molecules showing communication between cells different between people w…

This study is a double-blind, randomized, placebo-controlled trial to evaluate the use of high frequency TENS for pain control during IUD insertion. Transcutaneous electrical nerve stimulation (TENS) is a relatively low-cost, low-risk, non-pharmacologic intervention for pain mana…