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127005 trials found · Page 6217 of 6351
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Healthy volunteers needed to test safety of experimental drug KLA478
Knowledge-focused Recruiting nowThe purpose of this study is to evaluate the safety and tolerability and pharmacokinetics of single doses of KLA478 in healthy volunteers;
Phase 1 • Sponsor: Hunan Kelun Pharmaceutical Co., Ltd. • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:37 UTC
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New COPD inhaler spray tested in healthy volunteers – no cure expected
Knowledge-focused Stopped earlyGroups 1, 3, 4, 5 and 6 of this research team adopted a single-center, open-label design. Group 2 used a three-sequence, three-period crossover design, where participants in this dose group were randomly assigned to the three sequences in a 1:1:1 ratio to undergo three-period cro…
Phase 1 • Sponsor: Chia Tai Tianqing Pharmaceutical (Guangzhou) Co., Ltd. • Aim: Knowledge-focused
Last updated Aug 29, 2026 00:00 UTC
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Italian doctors quizzed on end-of-life law in children's ICUs
Knowledge-focused Not yet recruitingThis study aims to investigate pediatric intensive care providers' knowledge, perceptions, and experiences with Law 219/2017 by means of a national multicentric non-interventional cross-sectional study.
Sponsor: University of Padova • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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Cancer consent study pulled before it began
Knowledge-focused CancelledThis is a study to evaluate the impact of evidence-based visual key information (VKI) pages on participant's experiences with informed consent for research, enrollment in high-accruing studies that choose to use VKIs as part of their consent process, and research team perceptions…
Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC
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Laser showdown: does light therapy tweak nerves in healthy people?
Knowledge-focused Not yet recruitingStudy title: Comparative Effect of High-Level Versus Low-Level Laser Therapy on Nerve Root Function Among Healthy Young Adults: A Randomized Controlled Trial You are invited to participate in a research study to investigate the short-term effect of high-intensity laser therapy (H…
Sponsor: Taif A. M. Omran • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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New drug ABBV-547 enters first human safety trial
Knowledge-focused OngoingThe purpose of this study is to assess how safe, effective, and tolerable ABBV-547 is in adult participants in the United States and Japan. There will be 2 parts to this study. In Part 1, participants are placed in one of 7 groups where they will receive ABBV-547 at different do…
Phase 1 • Sponsor: AbbVie • Aim: Knowledge-focused
Last updated Jul 26, 2026 00:00 UTC
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Pfizer checks if migraine drug versions match up
Knowledge-focused CompletedThe purpose of this study is to assess the bioequivalence (medicines that may have different names or be made in different ways, but have the same effect on the body) of different formulations of a CGRP receptor antagonist in healthy adult participants. The study is seeking part…
Phase 1 • Sponsor: Pfizer • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Healthy volunteers test how breakfast and heartburn pills change new drug levels
Knowledge-focused CompletedThis study is a phase 1, open-label, randomized, four-period crossover study to evaluate the effect of food and rabeprazole on the ZN-A-1041 tablet formulation in healthy male and female participants.
Phase 1 • Sponsor: Genentech, Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:31 UTC
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New drug SRK-439 tested for safety in healthy adults
Knowledge-focused Recruiting nowA phase 1 study to assess the safety, tolerability, pharmacokinetics, and pharmacodynamics of SRK-439 in healthy adults
Phase 1 • Sponsor: Scholar Rock, Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC
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Promising psoriasis drug study for rare muscle disease pulled before start
Disease control CancelledBackground: Dermatomyositis (DM) and juvenile dermatomyositis (JDM) are diseases that weaken the immune system. DM and JDM can affect the muscles, skin, joints, and lungs and cause skin rashes and muscle inflammation. Symptoms include weakness, pain, fatigue, and rash. Not every…
Phase 2 • Sponsor: National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) • Aim: Disease control
Last updated Jun 27, 2026 07:59 UTC
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Vibrating platforms change reflex timing, small study finds
Knowledge-focused CompletedThis study examines how different standing postures and whole-body vibration conditions affect spinal reflex activity. Participants will stand in various positions-with and without vibration of two amplitudes-and H-reflex responses from the soleus muscle will be recorded. Additio…
Sponsor: Istanbul Physical Medicine Rehabilitation Training and Research Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Healthy men test new drug in Early-Stage safety trial
Knowledge-focused Stopped earlySingle-rising dose (SRD) part: The main objectives of the SRD part of this trial are to investigate safety, tolerability, and pharmacokinetics (PK) of BI 3009947 in healthy participants following oral administration of single rising doses. Bioavailability (BA) part: The main o…
Phase 1 • Sponsor: Boehringer Ingelheim • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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Healthy men test drug interaction: vimseltinib and metformin
Knowledge-focused CompletedThe main purpose of this study is to evaluate the effect of multiple doses of vimseltinib on the pharmacokinetics (PK) of a clinical OCT2 substrate (metformin) in healthy male participants. This study will also assess the safety and tolerability when vimseltinib is co-administere…
Phase 1 • Sponsor: Deciphera Pharmaceuticals, LLC • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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Puzzle power: can games help nurses learn IV safety?
Knowledge-focused CompletedThis study aims to evaluate the effect of puzzle-based education on nursing students' knowledge level, knowledge retention, and learning motivation regarding safe intravenous therapy practices. Intravenous therapy is a common but complex clinical procedure that requires accurate …
Sponsor: Aydin Adnan Menderes University • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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Healthy volunteers help uncover drug interactions
Knowledge-focused CompletedResearchers want to learn about calderasib when given with rosuvastatin and metformin in healthy people. The goal of this study is to compare the amount of rosuvastatin and metformin in a person's body over time when given with and without calderasib
Phase 1 • Sponsor: Merck Sharp & Dohme LLC • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Game on: puzzles vs kahoot in midwifery classrooms
Knowledge-focused CompletedThe aim of this study is to compare the effects of puzzle-solving and Kahoot-based learning methods on learning motivation and gaming experience among second-year midwifery students, and to evaluate students' satisfaction levels regarding these methods. The study is designed as a…
Sponsor: Agri Ibrahim Cecen University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:09 UTC
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Period pain may throw off your balance, new study suggests
Knowledge-focused Recruiting nowThe purpose of the study is to assess knee joint position sense, pain and dynamic balance in female with primary dysmenorrhea.
Sponsor: Cairo University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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New drug YN001 begins first human tests
Knowledge-focused Recruiting nowThis is a Phase 1, single-center, open-label study designed to evaluate the pharmacokinetics (PK), safety, and immunogenicity following a single dose administration in healthy adult volunteers.
Phase 1 • Sponsor: Beijing Inno Medicine Co., Ltd. • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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New eye drop put to the test in healthy volunteers
Knowledge-focused Recruiting nowThis Phase I study is designed to evaluate the safety, tolerability, and pharmacokinetic profile of BT01001 Ophthalmic Solution in healthy adult volunteers. The primary objectives are to assess the safety and tolerability of single and multiple ascending doses and to characterize…
Phase 1 • Sponsor: Beyang Therapeutics Co., Ltd. • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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Which airway device works best for seniors? new study aims to find out.
Knowledge-focused CompletedThis study compares the airway sealing pressure between I-gel® and I-gel plus® in elderly patients (aged 65-85) undergoing general anesthesia. I-gel® is a supraglottic airway device with a non-inflatable cuff, and I-gel plus® is an improved version with a larger gastric drainage …
Sponsor: Dongguk University International Hospital • Aim: Knowledge-focused
Last updated Jul 12, 2026 00:00 UTC