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127005 trials found · Page 6166 of 6351
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Scientists dive deep into the biology of obesity
Knowledge-focused Recruiting nowThis study will describe the phenotype (physical and behavioral traits) of overweight and obese people. It will characterize the hormones, metabolism, food preferences, fitness and physical activity levels, sleep patterns and thought processes in people with and without weight pr…
Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) • Aim: Knowledge-focused
Last updated Sep 03, 2026 00:00 UTC
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Protein and weight loss: what happens to your bones?
Knowledge-focused CompletedThe purpose of this study is to learn how the amount of protein during moderate weight loss influences bone health. We will also examine how two levels of protein intake affects diet quality.
Sponsor: Rutgers University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:33 UTC
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Can losing weight weaken your bones? new study investigates
Knowledge-focused CompletedThe purpose of this study is to determine the effect of weight loss on bone health in men.
Sponsor: Rutgers University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:34 UTC
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Scientists hunt for genetic clues in prostate cancer blood samples
Knowledge-focused Recruiting nowBackground: * It is not fully understood why prostate cancer in some men becomes androgen-independent (no longer responds to anti-androgen medication), but genetics likely plays an important role. * Genes contain the hereditary information that is passed down from parents to chi…
Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated Sep 03, 2026 00:00 UTC
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Study probes Men's fears about penile injections after surgery
Knowledge-focused CompletedThe purpose of this study is to help us understand more about your experience with penile injection therapy. Many men become anxious when thinking about penile injections. We would like to understand more about this anxiety. You will be asked to fill out questionnaires before you…
Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Salt mystery in POTS: do kidneys hold the key?
Knowledge-focused OngoingThe investigators will test the hypothesis that patients with chronic orthostatic intolerance or postural orthostatic tachycardia syndrome (OI or POTS) will be unable to conserve urinary sodium as compared to healthy control subjects.
Sponsor: Vanderbilt University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC
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Alcohol-Dependence drug studied in DUI offenders – study halted early
Disease control Stopped earlyAcamprosate will be given to approximately 30 DUI Court participants for 3 months and outcomes will be monitored. The hypothesis is that acamprosate will be safe and well-tolerated and that subjects' craving and other symptoms related to addiction will improve over time.
Sponsor: University of Oklahoma • Aim: Disease control
Last updated Jun 27, 2026 12:04 UTC
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A vast data bank could unlock secrets of bone and muscle diseases
Knowledge-focused Recruiting nowData involving orthopaedic conditions and rehabilitation aspects of musculoskeletal and neuromuscular disorders will be collected and stored as part of the normal clinical care of patients seen in the University of Florida (UF) and Shands Orthopaedics and Sports Medicine Institut…
Sponsor: University of Florida • Aim: Knowledge-focused
Last updated Sep 05, 2026 00:00 UTC
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Deep sleep or light nod? study probes best sedation for gallstone procedure
Knowledge-focused CompletedEndoscopic retrograde cholangiopancreatography (ERCP) for common bile duct stones (CBDS) removal can be performed under varying levels of sedation. Deeper sedation has been associated with more successful cannulation, but little is known about the efficacy of ERCP measured as rat…
Sponsor: Karolinska Institutet • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC
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Largest skin lupus database aims to uncover disease patterns
Knowledge-focused Recruiting nowThe Cutaneous Lupus Erythematosus (CLE) database, established in 2006, is a multi-site database between the University of Pennsylvania and the University of Texas Southwestern (UTSW).
Sponsor: University of Pennsylvania • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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French region screens 800 for bone disease
Knowledge-focused CompletedThe purpose of this study is to estimate Osteoporosis' prevalence in France and is a pilot study in the Department of the Alpes-Maritimes.
Sponsor: Centre Hospitalier Universitaire de Nice • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Scientists use advanced scanners to peek at Brain's chemical messengers
Knowledge-focused Recruiting nowThis study will use magnetic resonance spectroscopy (MRS) to measure in the brain the transfer of \[13\]C as it is naturally metabolized from glucose to specific chemical transmitters. From this method, we can measure the rate of production of an important excitatory neurotransmi…
Sponsor: National Institute of Mental Health (NIMH) • Aim: Knowledge-focused
Last updated Aug 30, 2026 00:00 UTC
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Massive screening effort seeks volunteers for addiction research
Knowledge-focused CompletedBackground: \- The Neuroimaging Research Branch of the National Institute on Drug Abuse (NIDA) is interested in developing a pool of potential research participants who may be eligible for research studies on drug abuse and addiction, pharmacological and psychosocial therapies f…
Sponsor: National Institute on Drug Abuse (NIDA) • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:03 UTC
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Cancer Patients' samples fuel future discoveries
Knowledge-focused Recruiting nowRATIONALE: Collecting and storing samples of tissue and blood from patients with cancer to test in the laboratory may help the study of cancer in the future. PURPOSE: This research study is collecting and storing tumor, tissue, and blood samples from patients with pancreatic can…
Sponsor: University of Arizona • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC
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Water pressure: can a second glass still boost blood pressure?
Knowledge-focused OngoingWe are studying the effects of oral water ingestion in patients with orthostatic hypotension. In this study, we are testing the null hypothesis that the blood pressure increase with oral water ingestion will not be diminished if a full prior water dose is given a few hours earlie…
Sponsor: Satish R. Raj • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC
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Can a glass of water or a change in posture spike your eye pressure?
Knowledge-focused By invitation onlyOur experiments are designed to test the overall hypothesis that position-dependent or water-dependent intra-ocular pressure (IOP) spikes occur in humans, and that these challenge ocular homeostasis.
Sponsor: Vanderbilt University Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC
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Building a better understanding of Low-Grade ovarian cancer
Knowledge-focused Recruiting nowThis study collects information to maintain a database on patients with low-grade ovarian or peritoneal tumors. Collecting information about the type of cancer and treatment, as well as details about follow-up care, may help researchers learn and better understand these tumor typ…
Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Aug 12, 2026 00:00 UTC
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Asthma attack study halted: what we almost learned
Knowledge-focused Stopped earlyThe purpose of this study is to identify the causes of asthma that were not previously suspected, to better understand the effects of inhaled steroids on asthma and to identify new way to treat asthma.
Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Diabetes and vitamin c loss: scientists launch major study to solve the mystery
Knowledge-focused Recruiting nowSeveral studies have reported that diabetic subjects have lower plasma vitamin C concentrations than non-diabetic subjects. Although urinary vitamin C loss in diabetic subjects was reported to be increased in two studies, these are difficult to interpret due to lack of controlled…
Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) • Aim: Knowledge-focused
Last updated Sep 02, 2026 00:00 UTC
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Anesthesia study probes brain waves during surgery
Knowledge-focused CompletedSevoflurane is widely used for induction of anaesthesia. Several studies showed EEG abnormalities during mask induction with sevoflurane. The aim of our study was to test the induction target concentration of sevoflurane on the spikes wave occurrence.
Sponsor: University Hospital, Bordeaux • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC