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127005 trials found · Page 6161 of 6351
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Biopsy clues: will the new kidney work?
Knowledge-focused CompletedThe purpose of this study is to see if substances measured in a small piece of the donor organ predicts how well the organ will function in the recipient after transplant. We will be testing blood, urine, and biopsy tissue samples in this study. The research team will be looking …
Sponsor: Weill Medical College of Cornell University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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Hip implant showdown: which stem saves more bone?
Knowledge-focused CompletedThis is a monocentric, prospective, randomized clinical survey to verify if the periprosthetic remodelling brought about either the AMIStem or the Quadra femoral component is equivalent.
Sponsor: Medacta International SA • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC
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Baby formula study: new blends may improve digestion
Knowledge-focused Completed* The primary objective of the study was to compare stool composition (stool soap and non-soap fatty acids, total fatty acids, minerals, and other stool constituents) of infants randomized to receive either standard formula, or 1 of 2 innovative formulas containing a new fat blen…
Sponsor: Société des Produits Nestlé (SPN) • Aim: Knowledge-focused
Last updated Aug 01, 2026 00:00 UTC
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MRI scans reveal hidden spinal cord changes in neck arthritis patients
Knowledge-focused CompletedThis study aims at evaluating spinal cord structure using diffusion tensor imaging in patients with cervical spondylosis.
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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10 drugs, 10 volunteers: scientists map Body's drug processing
Knowledge-focused CompletedThe study aims to descibe the pharmacokinetics of 10 substrates of enzymes involved in drug metabolism and their metabolites, after administration singly and simultaenously at predefined doses in 10 health volunteers.
Phase 1 • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Jun 26, 2026 13:16 UTC
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Ultrasound may take the guesswork out of wrist blood draws
Knowledge-focused CompletedThe investigators aim to determine if ultrasound guidance results in improved technique when drawing blood via a radial artery puncture.
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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Tiny trial on preventive bladder sling halted early — no clear answers
Prevention Stopped earlyNowadays the clinical significance of an occult stress urinary incontinence and its optimal treatment is not known.Regarding treatment, there are 2 main approaches : either the systematic preventive treatment of the occult stress urinary incontinence by means of a tension free va…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Prevention
Last updated Jun 28, 2026 00:00 UTC
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Massive data collection aims to unlock secrets of lung disease
Knowledge-focused Recruiting nowPulmonary hypertension (PH) is defined as a pulmonary arterial mean pressure (meanPAP) ≥ 25 mmHg measured in the right heart catheterization. There are different forms of PH defined in the classification of Dana Point 2008. PH is diagnosed with right heart catheterization but t…
Sponsor: Medical University of Graz • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC
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NICU donor milk study checks if guidelines are being followed
Knowledge-focused CompletedHuman milk is associated with substantial benefits to infants' health and development, especially in premature infants. Some mothers are unable or unwilling to provide breast milk to their infant. The use of donor human milk as an alternative to cow milk in these infants has rise…
Sponsor: Baylor College of Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Iron overload and gum health: new study explores the link
Knowledge-focused CompletedPeriodontitis is a chronic inflammatory disease that affects tissues surrounding the teeth. It is strongly associated with the major pathogenic "red complex", including Porphyromonas gingivalis, Tannerella forsythia and Treponema denticola1 and thus is considered an infection. Re…
Sponsor: Rennes University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:07 UTC
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New brain imaging methods could sharpen diagnosis of neurological diseases
Knowledge-focused OngoingMagnetic resonance spectroscopy (MRS) allows non-invasive measurement of the concentration of up to 18 metabolites in the brain ("neurochemical profile"). The objective of this proposal is to develop new methods for high-field brain MRS (3 to 7 Tesla). Our main hypothesis is th…
Sponsor: University of Minnesota • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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Thousands monitored in major IVC filter safety registry
Knowledge-focused Recruiting nowA prospective data registry for all patients who undergo IVC (Inferior Vena Cava) filter placement or retrieval at Stanford. Potential enrollees will already be undergoing the procedure. If patients are willing, they will be prospectively enrolled prior to the procedure. As part …
Sponsor: Stanford University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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Asthma study seeks volunteers to build research database
Knowledge-focused PausedThis study is designed to characterize subjects in terms of the nature and severity of their asthma and in terms of conditions that may alter the clinical expression of asthma. Some features will be obtained in all subjects. These include a medical history and baseline lung funct…
Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated Aug 16, 2026 00:00 UTC
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French hospitals track spleen injury care to find best practices
Knowledge-focused CompletedDescriptive, prospective, multicenter evaluation of spleen injury treatment in the Languedoc Roussilon region according to trauma severity, morbi-mortality and length of hospitalization.
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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Neck disc device study halted after just 2 patients
Disease control Stopped earlyThis study will be a non-randomized trial consisting of patients with single level (C3 to C7) symptomatic cervical disc disease who have not previously received fusion surgery at the same level, and have failed to improve with conservative treatment for at least 6 weeks prior to …
Sponsor: NuVasive • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC
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Pregnancy's final month: a natural blood thinner?
Knowledge-focused CompletedThe objective is to compare women's platelet answer in the last month of pregnancy to women old enough to procreate, no pregnancy and without hormonal treatment. The hypothesis of research is that the decrease of platelet answer in pregnant women could not only limit the occuren…
Sponsor: University Hospital, Toulouse • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC
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Costly drug may save money in severe childbirth bleeding, but study cut short
Knowledge-focused Stopped earlyThe main objective of this project is to assess the average cost of the treatment of bleeding postpartum with recombinant activated factor VII (NovoSeven®) and compare it to the reference strategy. Costs related to medicine NovoSeven® can generate surplus, but it also avoids in s…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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New ultrasound technique aims to better measure liver health
Knowledge-focused CompletedLiver stiffness measurement (LSM) by non invasive methods is increasingly used to estimate liver fibrosis in patients with chronic liver diseases. However, there is growing evidence that fibrosis is not the only determinant of liver stiffness. Indeed inflammation, cholestasis, co…
Sponsor: University Hospital, Bordeaux • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:33 UTC
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Could your genes make labor harder? new study investigates
Knowledge-focused Stopped earlyDespite the fact that a link between cholesterol and the myometrium has been clearly established, no study investigating aspects of cholesterol metabolism and uterine dystocia currently exists. This study is a pilot study whose aim is to test the hypothesis that an association be…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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New study reveals how many kids suffer pain months after surgery
Knowledge-focused CompletedThis study aims to estimate prevalence and determine risk factors for chronic pain at 3 months post-operative in pediatric surgery.
Sponsor: University Hospital, Bordeaux • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC