10 drugs, 10 volunteers: scientists map Body's drug processing

NCT ID NCT01188525

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study gave 10 healthy volunteers a single dose of 10 common drugs at the same time to see how their bodies break them down. The goal was to measure key factors like drug levels and half-life to understand each person's unique metabolic profile. The results could help personalize medicine in the future.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

10 common drugs (acetaminophen, caffeine, dextromethorphan, digoxin, memantine, midazolam, omeprazole, repaglinide, rosuvastatin, tolbutamide)

What this could lead to

If successful, this could help doctors personalize drug dosing based on a person's unique metabolism, reducing side effects and improving treatment effectiveness.

What could go wrong

This is a very small, early-phase study in just 10 healthy people. It only measures how drugs are processed, not whether they work for any disease. Results may not apply to sick patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Center of clinical investigation

    Paris, 75018, France