10 drugs, 10 volunteers: scientists map Body's drug processing

NCT ID NCT01188525

Completed Knowledge-focused Sponsor: Institut National de la Santé Et de la Recherche Médicale, France Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study gave 10 healthy volunteers a single dose of 10 common drugs at the same time to see how their bodies break them down. The goal was to measure key factors like drug levels and half-life to understand each person's unique metabolic profile. The results could help personalize medicine in the future.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: 10 common drugs (acetaminophen, caffeine, dextromethorphan, digoxin, memantine, midazolam, omeprazole, repaglinide, rosuvastatin, tolbutamide)
What this could lead to: If successful, this could help doctors personalize drug dosing based on a person's unique metabolism, reducing side effects and improving treatment effectiveness.
What could go wrong: This is a very small, early-phase study in just 10 healthy people. It only measures how drugs are processed, not whether they work for any disease. Results may not apply to sick patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEALTHY VOLUNTEERS

Contacts and locations

Locations

Center of clinical investigation

Paris, 75018, France

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