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127005 trials found · Page 6138 of 6351
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New MRI technique maps liver blood flow in 3D
Knowledge-focused CompletedThe objective of the project is to establish the 3D velocity mapping of the hepatic vasculature and its consistency
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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Blood protein may help ER spot serious headaches
Knowledge-focused CompletedThe main objective of this pilot study is to make a first assessment of the discriminating ability of a dosage of S100B protein for differential diagnosis between primary headaches and secondary headaches. For this, the investigators will compare serum S100B protein between two …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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Eye disease study tracks vision loss over years
Knowledge-focused CompletedBackground: Age-related macular degeneration (AMD) affects the macula in the eye. This is the central part of the retina. It is needed for sharp, clear vision and activities like reading and driving. AMD is the leading cause of vision loss in Americans 60 years of age and older.…
Sponsor: National Eye Institute (NEI) • Aim: Knowledge-focused
Last updated Aug 30, 2026 00:00 UTC
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Stretchy skin may reveal heart risks in rare genetic condition
Knowledge-focused CompletedBackground: Williams Syndrome (WS) is a genetic disorder. People with WS have less of a protein that allows parts of the body to stretch than other individuals. Researchers are interested in the stretchiness of the skin of people with WS and how it may relate to cardiovascular p…
Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Knowledge-focused
Last updated Aug 15, 2026 00:00 UTC
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Scientists probe muscle mysteries in cancer weight loss
Knowledge-focused Completedthe aim is to study skeletal muscle metabolism alterations métaboliques associated with weight loss in women with ovarian and/or endometrial cancer according to BMI.
Sponsor: University Hospital, Tours • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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Jaw surgery paste under scrutiny: does it raise infection risk?
Knowledge-focused CompletedThe goal of this study is to determine if the use of calcium phosphate paste in mandibular lengthening surgery causes more complications as surgical site infections and hardware removal. An evaluation will be made to determine if the benefits of the use of the paste (3D-stabilit…
Sponsor: Universitair Ziekenhuis Brussel • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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Heart condition costs under the microscope in massive hospital study
Knowledge-focused CompletedCardiomyopathy is the most common inherited cardiovascular disease, showing family aggregation, and it has a huge psychological and economic burden on family members. In this study, the investigators collected clinical information and costs of patients hospitalized with cardiomyo…
Sponsor: China National Center for Cardiovascular Diseases • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:35 UTC
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666 patients help doctors find best appendix closure method
Knowledge-focused Completedthis study compare between different types of appendicular stump closure
Sponsor: Zagazig University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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Metal-Free tooth implants put to the test
Disease control OngoingFirst, the surgical insertion of a ceramic (zirconia) dental implant will be performed in a single-tooth gap according to current state-of-the-art protocols. After a 3-months healing phase, a ceramic tooth replacement (a.k.a. implant crown) will be screw-retained on the implant a…
Sponsor: University of Bern • Aim: Disease control
Last updated Jun 27, 2026 12:09 UTC
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Join the ICARE registry to help scientists understand inherited cancer risks
Knowledge-focused Recruiting nowThe purpose of the Inherited CAncer REgistry (ICARE) Initiative is to provide individuals interested in participating in studies focused on inherited cancer predisposition the opportunity to enroll in a research registry. Efforts through the registry include, but are not limited …
Sponsor: Vanderbilt-Ingram Cancer Center • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:39 UTC
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Healthy hearts reveal aging secrets in new MRI study
Knowledge-focused CompletedIn normal ageing, the impact of myocardial fibrosis on myocardial function is unclear as diastolic function is reported to change according to age. The objective is to explore the relationship between myocardial function changes, with local (T1 and diffusion) fibrosis measures wi…
Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC
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Which graft is better for breast reconstruction? a Head-to-Head trial
Knowledge-focused CompletedBreast reconstruction after mastectomy has been shown to provide psychosocial benefits to breast cancer patients and is considered an integral part of breast cancer treatment. In general, breast reconstruction can be accomplished using the patients own tissues or implantable pros…
Sponsor: Ottawa Hospital Research Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Scientists map immune cells in colon cancer patients
Knowledge-focused CompletedDuration of each part of the study per patient: * Screening: From 1 to 4 weeks * Sampling period (blood and tissue): 1 day * Follow-up by patient: 60 months * Total study duration by patient: 84 months * Total inclusion duration: 24 months * Total Follow-up duration: 60 months *…
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Which crown material is best for your molars? new study aims to find out
Knowledge-focused OngoingThis is a randomized, prospective clinical trial. The aim of the project is to assess the clinical performance of three types of tooth-supported crowns; monolithic high translucent colored zirconia, crowns of high-translucent colored zirconia with a mini-veneer buccally and crown…
Sponsor: Malmö University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:32 UTC
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ICU recovery data: what happens after critical care?
Knowledge-focused Stopped earlyRegistry database of intensive care patients. These data comprises of routine data including mobilization data and follow up assessments.
Sponsor: Technical University of Munich • Aim: Knowledge-focused
Last updated Jun 26, 2026 19:04 UTC
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Researchers test if CT scan tweaks change tumor readings
Knowledge-focused OngoingThe purpose of the study is to see how measurements of tumor differences vary with slight changes in CT scan parameters. Reproducible radiomic features can be extracted for abdominal tumors, and specifically colorectal liver metastases, imaged with clinical CT scanners even in th…
Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Tiny study probes why islet transplants prevent low blood sugar
Knowledge-focused CompletedTo determine the effect of sympathetic neural and hormonal (epinephrine) input on islet cell hormonal responses to insulin-induced hypoglycemia in type 1 diabetic recipients of intrahepatic islet transplantation. We hypothesize that α-adrenergic (neural) blockage will abolish ins…
Early phase 1 • Sponsor: University of Pennsylvania • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:25 UTC
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Newborn death prediction tool for early membrane rupture falls short
Knowledge-focused Stopped earlyPretern premature rupture of the membranes (PPROM) remains the leading cause of preterm deliveries and neonatal mortality and morbidity. PPROM is defined as rupture of the fetal membranes prior to 37 weeks' gestation. PPROM complicates 2-4% of all pregnancies and accounts for app…
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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Family videos may replace In-Person mobility tests for seniors
Knowledge-focused CompletedThe purpose of this research study is to find out if mobility (the ability to move around) can be reliably assessed by having the family or care giver caregiver take a video based test for the patient. If this study shows that mobility can be assessed by family or caregiver, this…
Sponsor: Wake Forest University Health Sciences • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC
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Can muscle oxygen levels explain chronic back pain?
Knowledge-focused CompletedThe study evaluate paraspinal aerobic metabolism of chronic low back pain patients and healthy people during an original and standardized isokinetic protocol. The aim of this study is to determine a potential alteration of muscular aerobic metabolism in low back pain patients, i…
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC