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127005 trials found · Page 6123 of 6351
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Does anesthesia flow affect eye pressure? new study investigates
Knowledge-focused CompletedDifferent amounts of anesthetic gas can be used in the obstetric gynecological surgery operations to be performed with open method. Researchers aimed to compare the effect of gas changes on intraocular nerve diameter by ultrasonography.
Sponsor: Bursa Yuksek Ihtisas Training and Research Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC
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Thousands of heartburn patients to be tracked for years in major new study
Knowledge-focused By invitation onlyA multi-center, multi-year registry of patients with gastroesophageal reflux disease (GERD) undergoing diagnostic evaluation and/or treatment of GERD and associated diseases and complications.
Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated Aug 28, 2026 00:00 UTC
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App aims to get cancer survivors moving – but trial stopped early
Symptom relief Stopped earlyThis is a behavioral study that will examine changes in physical activity and vascular health in response to a digital tool (app) that will appear on participant's lock screen of their Android phone. Participants will be asked to use this app for 3 months and to wear a Fitbit dev…
Phase 1/2 • Sponsor: Penn State University • Aim: Symptom relief
Last updated Jun 27, 2026 09:08 UTC
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Ear zapper aims to replace opioids for vomiting syndrome
Symptom relief Stopped earlyWe hypothesize that 1) Neurostimulation via a novel auricular percutaneous electrical nerve field stimulation (PENFS) device is a safe, non-invasive opioid-sparing alternative therapy for severe abdominal pain, nausea, and vomiting associated with CVS and will reduce the need for…
Sponsor: Medical College of Wisconsin • Aim: Symptom relief
Last updated Jun 27, 2026 12:03 UTC
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Small study tests how oral ALS drug works in the body
Knowledge-focused CompletedTo evaluate the pharmacokinetics of single doses of edaravone oral suspension in Patients with Amyotrophic Lateral Sclerosis
Phase 1 • Sponsor: Shionogi • Aim: Knowledge-focused
Last updated Jul 17, 2026 00:00 UTC
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Hormone fluctuations may rewire muscle reflexes, study finds
Knowledge-focused CompletedThe goal of this project is to test our central hypothesis that changes in sex hormone concentration result in changes to the basic elements of motor control - at multiple levels, from the musculotendinous unit to motor control circuitry. Under Aim 1 the investigator will determi…
Sponsor: University of Texas Southwestern Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC
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New camera could see blood flow in your skin
Diagnosis CompletedThe purpose of this study is see fi the hyperspectral camera system (HCS) can measure skin blood flow (perfusion and oxygenation) in healthy people.
Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Diagnosis
Last updated Jun 27, 2026 08:04 UTC
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Hybrid heart fix combines bypass and stents – but study stalls
Disease control Stopped earlyThis study evaluated the effectiveness and safety of Hybrid Coronary Revascularization in real-world practice.
Sponsor: Seung-Jung Park • Aim: Disease control
Last updated Jun 27, 2026 12:07 UTC
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Stage your way to better health: UC davis tests theater as a teaching tool
Knowledge-focused OngoingThis study evaluates the feasibility and the potential positive health impacts of a novel "health education theater," which will task participants of a health education program to create an original 10-minute theater that is required to use the health guidelines about physical ac…
Sponsor: University of California, Davis • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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Study digs into medical records to uncover clues about delayed breathing tube removal
Knowledge-focused CompletedTimely removal of a breathing tube after surgery is an important part of recovery for patients admitted to the intensive care unit (ICU). In some cases, patients may require longer use of mechanical ventilation, which can be associated with longer hospital stays and a higher risk…
Sponsor: Kaohsiung Armed Forces General Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:01 UTC
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Researchers track real-world safety of haemophilia b drug over nearly a decade
Knowledge-focused By invitation onlyThis study will collect information on side effects and how well Refixia/REBINYN works during long-term treatment (prophylaxis) in males with haemophilia B. While taking part in this study, participants will receive the same treatment as given to them by their study doctor. All v…
Sponsor: Novo Nordisk A/S • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:06 UTC
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New tool aims to measure brain injury recovery confidence
Knowledge-focused Stopped earlyThe purpose of this study is to validate the Brain Injury Self-Efficacy Scale as a measure of self-efficacy in brain injury by comparing it with other measures of self-efficacy, the GSE, and PROMIS self-efficacy.
Sponsor: Rehabilitation Hospital of Indiana • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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Which stitch heals best? spine surgery wound study seeks answers
Knowledge-focused CompletedThe Researchers are trying to determine if there is a difference in blood flow around a wound site when comparing three different types of wound closure techniques.
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:08 UTC
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Skin test could warn of hidden blood vessel trouble
Knowledge-focused Stopped earlyMany acute and chronical medical conditions, such as, shock, sepsis, diabetes, hypertonia, and cardiovascular disease are associated with a perturbated or lost ability of regulating the diameter of the blood vessels. These changes in regulatory function can be seen especially in …
Sponsor: University Hospital, Linkoeping • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:33 UTC
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Gut bacteria differences found in IBD and Parkinson's patients
Knowledge-focused CompletedInflammatory bowel diseases (IBD) and Parkinson disease (PD) are complex and multifactorial pathologies. Gut microbiota seems to play an active role. Indeed the digestive microbiota of patients with IBD or PD exhibits different compositions compared with asymptomatic subjects. B…
Sponsor: Hôpital Européen Marseille • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:27 UTC
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Better eye redness checks for contact lens users?
Knowledge-focused CompletedSoft Contact Lens (SCL) use all over the world is still increasing. Ocular surface inflammatory reaction is the most common risk of using SCL. Currently, the standard used to assess this complication is the Efron Degree System (EDS), but it has high variability due its subjectivi…
Sponsor: Indonesia University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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Scientists seek to unlock the Brain's secrets of sight and sound
Knowledge-focused Recruiting nowBackground: When people see and hear, the brain changes signals from the eyes and ears into perceptions and thoughts. No one fully understands how this happens. Researchers want to explore how healthy brains process sights and sounds. Objectives: To explore how people understa…
Sponsor: National Eye Institute (NEI) • Aim: Knowledge-focused
Last updated Sep 09, 2026 17:00 UTC
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Experimental heart valve device tested in just one patient — study halted
Disease control Stopped earlyThis study is to evaluate the safety and technical performance of the Cardiovalve Transfemoral Mitral Valve System with its associated procedure, to minimize mitral regurgitation. Data collected in this clinical study will include 30-day safety and performance of the device and d…
Sponsor: Cardiovalve Ltd. • Aim: Disease control
Last updated Jun 27, 2026 14:01 UTC
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Small study probes dangerous duo: opioids and sedatives
Knowledge-focused CompletedThis study will examine the effects of doses of opioid/placebo and doses of sedative/placebo, alone and in combination. The primary outcomes are related to pharmacodynamic measures (subjective ratings of drug liking and other abuse-related effects; physiological outcomes) to dete…
Phase 1 • Sponsor: Sharon Walsh • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:55 UTC
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Sitting too much may harm your blood vessels – study investigates why
Knowledge-focused CompletedProlonged periods of reduced activity are associated with decreased vascular function and muscle atrophy. Physical inactivity due to a sedentary lifestyle or acute hospitalization is also associated with impaired recovery, hospital readmission, and increased mortality. Older adul…
Sponsor: University of Utah • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC