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127005 trials found · Page 6101 of 6351
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3,000 RA patients to donate blood for future breakthroughs
Knowledge-focused By invitation onlyThe Biorepository is a prospective observational cohort study for patients under the care of a licensed physician or qualified physician extender. Target minimum enrollment is approximately 3,000 patients within the first 5 years of the study with no defined upper limit of enroll…
Sponsor: CorEvitas • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC
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Researchers review best acyclovir dose for obese patients with rare brain infection
Knowledge-focused CompletedMulticenter retrospective chart review of patients admitted to any of the six study centers (SSM Health - St. Clare, St. Mary's, Saint Louis University Hospital, St. Anthony's, St. Mary's Madison, Rush University Medical Center, or Methodist Dallas Medical Center) between January…
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Stroke mimics: new study follows patients without stroke to uncover hidden patterns
Knowledge-focused CompletedFunctional neurological disorders are an important subgroup of patients with stroke mimics admitted to stroke unit.Their clinical profile and outcome are poorly known. The goal of this study is to describe the cognitive and behavioral profile of stroke mimics patients, without ev…
Sponsor: Fondation Ophtalmologique Adolphe de Rothschild • Aim: Knowledge-focused
Last updated Aug 30, 2026 00:00 UTC
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Could your diet trigger kidney stones by changing your immune system?
Knowledge-focused CompletedThis study will test whether oxalate stimulates urinary crystals and impacts the immune system in healthy subjects using two controlled diets (low and high oxalate).
Sponsor: University of Alabama at Birmingham • Aim: Knowledge-focused
Last updated Jun 28, 2026 00:00 UTC
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Dental implant crown attachment method may influence gum inflammation
Knowledge-focused CompletedThis study aims to examine the inflammatory response mediated by MMP-8 (Matrix metalloproteinase-8 ) level in peri-implant sulcus fluid adjacent to screw-retained, cemented or using the Acuris-system fixed single implant crowns as well as changing of the marginal bone level withi…
Sponsor: Medical University of Graz • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Online therapy for stressed teens with chronic conditions shows promise, but study cut short
Symptom relief Stopped earlyThis study aims to test the effectiveness of a 6-week long virtual Acceptance Commitment group therapy as a non-pharmaceutical intervention to improving other functional outcomes for adolescents with a chronic medical condition in comparison to no treatment.
Sponsor: Children's Hospital Los Angeles • Aim: Symptom relief
Last updated Jun 27, 2026 12:09 UTC
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Fatty liver disease packs a punch on wallets in flanders
Knowledge-focused CompletedTo determine the economic burden of NAFLD (Non-Alcoholic-Fatty-Liver Disease) patients in Belgium, Flanders by means of a bottom-up approach.
Sponsor: Hasselt University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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Can nurse practitioners and physician assistants ease pressure on emergency rooms?
Knowledge-focused CompletedThis study will explore the result of different skill-mix in ED/UTCs in England, to make recommendations about the best balance. Patient and public involvement (PPI) representatives have helped design the study. There will be an independent PPI panel who can feed in their views …
Sponsor: Kingston University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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Scleroderma mystery: could a simple hormone be involved?
Knowledge-focused CompletedSystemic sclerosis is an autoimmune and inflammatory disease characterized primarily by fibrosis and vascular involvement. We know that the immune system is disrupted in systemic sclerosis, but there are probably other mechanisms to explain the disease, including deregulation of …
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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New study tests simpler heart monitoring for kids under anesthesia
Knowledge-focused CompletedThis prospective observational pilot study evaluates agreement between Ultrasound Cardiac Output Monitor (USCOM) measurements and transthoracic echocardiography-derived hemodynamic parameters in pediatric patients under standardized general anesthesia prior to surgical incision. …
Sponsor: Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC
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Toxicology study sheds light on chemical submission cases
Knowledge-focused CompletedThe purpose of this study is to carry out a systematic toxicological analysis of all the patients, examined at the UMJ of the Hôtel-Dieu following a complaint for suspected chemical submission. By comparing the toxicological data with the clinical examination data (e.g. treatment…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:06 UTC
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Do you really need sterile gloves for wound care? small study investigates
Knowledge-focused CompletedThis randomized interventional pilot study aims to compare the rate of significant Surgical Site Infection (SSI) within the six weeks after elective orthopedic surgery using sterile versus clean non-sterile glove postoperative dressing techniques.
Sponsor: Hamad Medical Corporation • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC
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Smart oxygen monitor may protect cells during rhinoplasty
Knowledge-focused CompletedThe aim of this study is to evaluate whether the use of Oxygen Reserve Index (ORİ) can prevent hyperoxia in patients undergoing rhinoplasty surgery and whether it can reduce oxidative stress caused by hyperoxia.
Sponsor: Dr. Lutfi Kirdar Kartal Training and Research Hospital • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:24 UTC
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Rethinking Pre-Surgery urine tests: could skipping a second culture be safe?
Knowledge-focused CompletedObjective: The current European Association of Urology (EAU) guidelines do not provide clear recommendations on whether patients with a positive urine culture(UC) should wait until the culture turns negative following antimicrobial treatment before undergoing percutaneous nephrol…
Sponsor: Junhao Zheng • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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Tiny organisms may hold clues to kidney disease
Knowledge-focused PausedThe purpose of the study is to identify bacterial and fungal microbiome associated with calcium oxalate (CO) urolithiasis and renal cell carcinoma (RCC).
Sponsor: University of Miami • Aim: Knowledge-focused
Last updated Aug 29, 2026 00:00 UTC
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Robot suit aims to help stroke survivors walk better
Symptom relief CancelledPrevious studies of the exosuit technology have culminated in strong evidence for the gait-restorative effects of soft robotic exosuits for patients post-stroke by means of substitution for lost function. The present study builds on this work by suggesting that an exosuit's immed…
Sponsor: Lou Awad, PT, DPT, PhD • Aim: Symptom relief
Last updated Jun 27, 2026 09:10 UTC
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Broccoli sprouts leave a signature in your body – scientists want to find it
Knowledge-focused OngoingThe purpose of this project is to study the molecular and metabolic profiles in human plasma, urine and microbiome composition following the consumption of broccoli sprouts.
Sponsor: Oregon State University • Aim: Knowledge-focused
Last updated Aug 09, 2026 00:00 UTC
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Could a simple calculation replace a complex testosterone lab test?
Knowledge-focused CompletedCurrently, the gold standard to obtain bioavailable testosterone results is radioimmunoassay (RIA). However, this assay requires specific equipment. Giton in 2006 proposed an optimized calculation of the Vermeulen equation, the results of which seem to be well correlated with th…
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:06 UTC
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Can lung pressure predict treatment needs in collapsed lung?
Knowledge-focused CompletedIntrapleural pressures have been shown to be a useful clinical predictor in pleural effusions, however it's utility has not been described in pneumothorax. Data on intrapleural pressures in pneumothorax are limited. Furthermore, the pleural pressure in tension pneumothorax is the…
Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:55 UTC
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Bone density may influence how athletes land after ACL repair
Knowledge-focused Stopped earlyThe purpose of this study is to look at the effects of bone density on lower extremity loading mechanics using Blood Flow Restriction (BFR) to provide the control group for bone health. Hypothesis: The BFR group will have decreased bone mineral loss and improved functional perfo…
Sponsor: Candice Dunkin, MS, LAT, ATC • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:33 UTC