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127005 trials found · Page 6083 of 6351
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Tiny study probes COVID antibodies in cystic fibrosis patients
Knowledge-focused CompletedCoronavirus disease 2019 (COVID-19) which is caused by the virus SARS-CoV-2 has resulted in an ongoing global pandemic. It is unclear whether the relatively low number of reported cases of COVID-19 in people with CF (pwCF) is due to enhanced infection prevention practices or whet…
Sponsor: Insel Gruppe AG, University Hospital Bern • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Brain bleed study halted: sodium Lactate's promise unproven
Disease control Stopped earlySubarachnoid hemorrhage by aneurysmal rupture is a serious condition associated with a high mortality rate. Among the complications presented by these patients, vasospasm is one of the main causes of secondary aggravation, in particular the appearance of delayed neurological defi…
Phase 3 • Sponsor: Centre Hospitalier Universitaire de Nice • Aim: Disease control
Last updated Jun 27, 2026 12:38 UTC
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X-Ray study tracks head movement during cancer radiation
Knowledge-focused CompletedThe primary objective of this observational study is to quantify the translation, rotation, and deformation of patient head positions of head and neck cancer patients over the course of a radiation therapy treatment for head and neck cancer. This objective will be achieved by com…
Sponsor: University of Sydney • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:35 UTC
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Jumping for science: plyometric workouts put to the test
Knowledge-focused CompletedThis retrospective study evaluated the effects of an eight-week lower body plyometric training program on serum creatine phosphokinase (CPK) and creatinine levels in male collegiate volleyball players. Sixty two players were divided into experimental and control groups. CPK and c…
Sponsor: Batterjee Medical College • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC
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Marfan study sheds light on spinal issues linked to dural ectasia
Knowledge-focused CompletedPrimary outcome is to compare the frequency and clinical features of spinal symptoms between Marfan patients with dural ectasia (cases) and those without (controls). 1. / Frequency of orthostatic headaches 2. / Frequency of low back pain due to orthostasis 3. / Frequency of low …
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:11 UTC
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New Fat-Targeting drug tested in healthy volunteers
Knowledge-focused CompletedThis Phase 2 study will be an open-label and single course study to assess the safety, tolerability, PK and metabolite profile of CBL-514.
Phase 2 • Sponsor: Caliway Biopharmaceuticals Co., Ltd. • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:36 UTC
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Tiny leg implant drug levels tracked in 7 patients
Knowledge-focused OngoingLIFE-BTK PK is a prospective, single-arm, open-label, non-blinded, non-randomized sub-study of LIFE-BTK Randomized Controlled Trial (NCT04227899), that will enroll approximately 7 subjects in the United States (US) and outside the US with a maximum of 5 sites in the US. Of the 7 …
Sponsor: Abbott Medical Devices • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:14 UTC
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Bleeding breakthrough fizzles: fibrinogen trial for chemo patients halted after just one patient
Disease control Stopped earlyPlatelet transfusions are widely employed to prevent or treat bleeding episodes in patients with thrombocytopenia. Patients with bone marrow failure secondary to haematological malignancy and chemotherapy frequently receive prophylactic platelet transfusion when platelet level re…
Phase 2 • Sponsor: Centre Hospitalier Universitaire de Saint Etienne • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC
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Laser vs. alcohol: which eye surgery method causes less haze?
Knowledge-focused Stopped earlysurgical correction of ametropia. A number of improvements have been introduced to overcome the side effects and complications such as corneal haze, epithelial irregularities induced by wound healing, pain and delayed visual acuity recovery associated with PRK surgery. During tra…
Sponsor: Fondation Ophtalmologique Adolphe de Rothschild • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Dementia agitation drug trial halted after just 5 patients
Symptom relief Stopped earlyA randomized, double-blind, placebo-controlled parallel group 3-arm study assessing efficacy, safety, and tolerability of two doses BXCL501 in male and female geriatric residents (65 years and older) with acute agitation associated with all forms of dementia (i.e., probably Alzhe…
Phase 2 • Sponsor: BioXcel Therapeutics Inc • Aim: Symptom relief
Last updated Aug 13, 2026 00:00 UTC
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Blood pressure drug may offer clues to chronic pain relief
Knowledge-focused OngoingThe purpose of this study (PASSION study) is to monitor symptoms of chronic pain before and after 2 weeks of a standard drug commonly used to treat elevated blood pressure compared with 2 weeks of placebo (crossover design) so that we may better understand how blood pressure affe…
Early phase 1 • Sponsor: University of Kansas Medical Center • Aim: Knowledge-focused
Last updated Aug 22, 2026 00:00 UTC
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New study tests safer ventilator monitoring for ICU patients
Knowledge-focused CompletedASOP is a prospective cohort study comparing three methods for assessing risk of self-induced lung injury in patients with acute respiratory failure being managed with pressure-support ventilation. We will describe the relationship between three different assessment methods for r…
Sponsor: Duke University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC
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Screen time and teen minds: new study probes link
Knowledge-focused By invitation onlyIntroduction: WHO defines youth as 15-24 years age group. At this stage, the brain is still under development, with high impulsiveness, being fond of stimulation and yearning for peer life. Compared with traditional interpersonal interaction, modern youths use the Internet as a m…
Sponsor: National Taiwan University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:39 UTC
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Thousands of youth workers surveyed to uncover hidden toll of trauma care
Knowledge-focused CompletedThe goal of this observational study is to understand how work-related stress and personal characteristics affect the wellbeing of adults who work with children and young people in youth care services in Flanders, Wallonia, France and The Netherlands. The study focuses on three a…
Sponsor: Vrije Universiteit Brussel • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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Text game reveals how depression shapes choices
Knowledge-focused CompletedThe purpose of the study is to evaluate the use of a text-based game as a way to understand decision making and knowledge related to anxiety, stress, and mood states like depression or loneliness. The investigators are interested in identifying whether participants who are given …
Sponsor: Bard College • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:06 UTC
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Web tool aims to boost HIV testing among black women in the south
Knowledge-focused Stopped earlyThe proposed intervention is a web-based intervention guided by theoretical components to increase HIV home testing among Black women at risk for HIV and sexually transmitted infections (STIs) in a HIV hotspot in the South. The intervention will promote using the home test, linka…
Sponsor: Johns Hopkins Bloomberg School of Public Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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Short survey aims to spark better doctor-patient talks
Knowledge-focused CompletedThis is a randomized controlled trial of the Patient-Initiated Note about Goals (PING).
Sponsor: Duke University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:55 UTC
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Snakes and ladders for hydration: fun game boosts Kids' water knowledge
Knowledge-focused CompletedThis study evaluated a six-week educational program designed to improve hydration knowledge, hydration status, and drinking practices in young school children in Tunisia. The intervention used an adapted "Snakes and Ladders" board game that delivers fun, age-appropriate messages …
Sponsor: The Higher Institute of Sport and Physical Education of Sfax • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC
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Sniffing or neutral? study tests best head position for Kids' airway devices
Knowledge-focused CompletedThe correct head position for airway management is considered as a mainstay of good clinical practice. The recommended head position for all patients is the horizontal position of the head with in tragus-to- sternal notch in line alignment. This could be achieved in infant (under…
Sponsor: Brno University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:36 UTC
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Night shifts may disrupt your metabolism and sleep, new study finds
Knowledge-focused CompletedIn an exploratory observational pilot study, the investigators will focus on the effects of short-term circadian misalignment induced by shift work on multidimensional measurements including glucose excursion, metabolic health, circadian rhythms (measured in vitro and in vivo), s…
Sponsor: Tinh-Hai Collet, MD • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC