Night shifts may disrupt your metabolism and sleep, new study finds

NCT ID NCT05177965

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
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Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This completed observational study looked at 72 men and women aged 20-50 who work rotating night and day shifts. Researchers measured blood sugar, weight, sleep patterns, and other health markers to understand how short-term circadian misalignment from shift work affects the body. The goal is to gather insights that could lead to better health recommendations for shift workers.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could help explain why shift work is linked to metabolic problems, pointing toward better health advice or interventions for shift workers.
What could go wrong
This is a small, exploratory observational study, not a clinical trial testing a treatment. It can show associations but cannot prove cause and effect, and results may not apply to all shift workers.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

72 people

The number who actually took part.

Started

Feb 2022

Finished

Aug 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Shift workers

Ages

20 to 50 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Men and women * Age 20-50 years * Working ≥ 80% full-time equivalent over the previous month and during the study * Working night shifts (i.e. shifts that comprise working hours between 23h and 06h) in rotation with day shifts (i.e. shifts that comprise working hours between 06h and 20h) * Planned to work at least 3 consecutive night shifts during the study preceded by at least a day off or day shift * Planned to work at least 3 consecutive day shifts during the study * Confident use of a smartphone compatible with the study application (iOS, Android) and able to regularly take pictures of consumed food/drinks * Able to give a fully informed consent and follow the study procedures Exclusion Criteria: * Planned or current pregnancy during the study * Menopausal women * Major illness or hospitalization over the previous month * Carries a pacemaker, pump or other medical device that can be disabled by a magnet * Major mental illness * Trip to a different time zone (≥ 2-hour time difference) over the previous month or planned during the study * Enrolled in an interventional clinical trial (potentially interfering with the main outcomes) over the previous month or planned during the study

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Geneva University Hospitals

    Geneva, 1211, Switzerland

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