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127005 trials found · Page 5845 of 6351
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New arabic jaw function test aims to improve care for TMJ disorders
Knowledge-focused Not yet recruitingThe purpose of this study is to test if the translated Arabic version of the (jaw functional limitation scale -8) JFLS\_8 , valid (face, content, feasibility) ,reliable (internal consistency, test retest) and culturally adapted enough to quantify the impact of temporomandibular j…
Sponsor: Cairo University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:11 UTC
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New Drug's heart safety checked in healthy volunteers
Knowledge-focused Recruiting nowThe aim of this trial is to evaluate the effect of a single oral dose of HDM1002 tablets on the QT/QTc interval in healthy subjects.
Phase 1 • Sponsor: Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:35 UTC
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Nurse training gets personal: study tests learning style grouping
Knowledge-focused Not yet recruitingProblem-based learning (PBL) is a learner-centered educational approach that helps nurses improve clinical skills through group discussion, case analysis, and collaborative problem-solving. However, the way participants are assigned to learning groups may influence how effectivel…
Sponsor: Shahid Beheshti University of Medical Sciences • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC
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Can an online course empower health workers to better guide minority women through menopause?
Knowledge-focused CompletedThe goal of the study is to examine the extent to which exposure to the SUPPORT prototype increases community health workers' (CHWs) knowledge, skills, and self-efficacy to conduct effective outreach to minority women experiencing the menopausal transition. The investigators will…
Sponsor: KDH Research & Communication • Aim: Knowledge-focused
Last updated Jul 11, 2026 00:00 UTC
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New lupus drug candidate begins first safety tests in humans
Knowledge-focused Not yet recruitingThis study is a Phase Ia, single-center, randomized, double-blind, dose-escalation, placebo-controlled clinical trial designed to evaluate the safety, tolerability, and pharmacokinetic/pharmacodynamic (PK/PD) profile of ACT100 in healthy participants. A total of 6 dose cohorts ar…
Phase 1 • Sponsor: Xiamen Amoytop Biotech Co., Ltd. • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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Exercise study reveals muscle secrets in older MS patients
Knowledge-focused Recruiting nowThe purposes of this study are to: 1) compare baseline muscle and cardiovascular health in older individuals (\>60 years old) diagnosed with MS to age-matched people without MS, 2) determine muscle and whole body changes to an exercise training program, 3) determine if the muscle…
Sponsor: Oklahoma Medical Research Foundation • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:02 UTC
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New pill CMS-D017 enters first human safety trials
Knowledge-focused Recruiting nowThis study is a first-in-human (FIH) trial of CMS-D017 conducted in healthy Chinese adult participants, consisting of two parts: Part 1-a single ascending dose (SAD) study (referred to as Part 1 SAD), and Part 2-a multiple ascending dose (MAD) study (referred to as Part 2 MAD). T…
Phase 1 • Sponsor: Shenzhen Kangzhe Biotechnology Co., Ltd. • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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Can peer mentors and videos ease nursing Students' first clinical shock?
Knowledge-focused CompletedThis randomized controlled study will aim to evaluate the effect of a peer-supported video and interaction-based clinical orientation program on reality shock and adaptation during the first clinical experience. The study will be conducted with nursing students who will start the…
Sponsor: Siirt University • Aim: Knowledge-focused
Last updated Jul 03, 2026 00:00 UTC
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Generic cariprazine put to the test: will it match the brand?
Disease control CompletedSingle dose oral bioequivalence study of Cariprazine 1.5 mg Hard Capsules (1.5 mg Cariprazine hydrochloride) and Reagila® 1,5 mg Hartkapseln (Hard Capsules) (Cariprazine) in healthy adult human participants under fasting conditions.
Phase 1 • Sponsor: Humanis Saglık Anonim Sirketi • Aim: Disease control
Last updated Jul 10, 2026 00:00 UTC
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New fatty liver drug tested in healthy volunteers – no cure expected
Knowledge-focused OngoingThis is a first time in Asia (FTIA) study designed to evaluate the safety, tolerability, pharmacokinetic (PK) and immunogenicity of efimosfermin alfa to healthy participants of Chinese, Japanese, and White/European ancestry.
Phase 1 • Sponsor: GlaxoSmithKline • Aim: Knowledge-focused
Last updated Jul 26, 2026 00:00 UTC
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Could racket sports boost lung rehab? small study tests feasibility
Symptom relief Recruiting nowThis study looks at whether Street Racket is a feasable activity that can be added to pulmonary rehabilitation for people with chronic lung disease. Participants complete short questionnaires at the start and end of the program to rate the feasibility and rate their breathlessnes…
Sponsor: Mona Lichtblau • Aim: Symptom relief
Last updated Jun 27, 2026 11:01 UTC
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Ankle fracture study: which surgery heals better?
Disease control Not yet recruitingThe aim of this study is to compare the short term : Clinical, radiographic and functional outcome, and healing time and rate of complications between fixation of lateral malleolar fracture in Danis\_Weber\_A\&B fracture ankle by plate versus intramedullary screw fixation
Sponsor: Sohag University • Aim: Disease control
Last updated Jun 27, 2026 11:01 UTC
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Nose surgery study: does drug dose tied to workload?
Knowledge-focused Not yet recruitingThis prospective observational cohort study aims to investigate whether the weight-based equivalent (mg/kg) of a fixed 1 g dose of tranexamic acid administered during septorhinoplasty is associated with intraoperative remifentanil titration frequency and perceived anesthesiologis…
Sponsor: Istinye University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:11 UTC
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Early study checks how food affects new drug AZD5004
Knowledge-focused CompletedThe purpose of this study is to assess the pharmacokinetics (PK), safety and tolerability of different oral formulations of AZD5004, and to evaluate the effect of food on these formulations in healthy participants.
Phase 1 • Sponsor: AstraZeneca • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:06 UTC
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Can better ICU processes save lives and money? huge study aims to find out
Knowledge-focused Recruiting nowThe aim of the study is to identify and evaluate incentive mechanisms for the implementation of quality-relevant care processes. The objective is to correlate adherence to individual process-based quality indicators or their combination with outcome data. In addition, cost shares…
Sponsor: Charite University, Berlin, Germany • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:02 UTC
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Stretching for musicians: a small study tests if mobility moves improve posture and balance
Knowledge-focused CompletedOrchestra musicians are exposed to prolonged asymmetric postures and repetitive upper-quarter loading that may affect postural control. This exploratory randomized controlled trial examined whether a four-week mobilization-based exercise program, delivered once or twice weekly, w…
Sponsor: Inonu University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:05 UTC
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New study tests Long-Wear comfort of daily contacts for astigmatism
Symptom relief Recruiting nowThe purpose of this study to assess the wear experience of people who have astigmatism when wearing a daily disposable contact lens for astigmatism over long days of wear.
Sponsor: Ohio State University • Aim: Symptom relief
Last updated Jun 27, 2026 12:00 UTC
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New artificial tears put to the test for dry eye sufferers
Symptom relief CompletedThe purpose of this study is to evaluate the safety and tolerability of two new artificial tear formulations in subjects with moderate dry eye disease.
Sponsor: Alcon Research • Aim: Symptom relief
Last updated Aug 13, 2026 00:00 UTC
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New probe aims to sharpen colonoscopy images
Knowledge-focused By invitation onlyThe goal of this study is to use a colonoscope compatible device capable of taking images of the lower gastrointestinal tract. The main question it aims to answer is: Is the colonoscope compatible optical coherence tomography probe (CC-OCT probe) an effective device to use to ta…
Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated Jul 15, 2026 00:00 UTC
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Syringe vs. pen: which delivers the drug better?
Knowledge-focused CompletedThe goal of this study is to find out whether different formulations of survodutide given by different delivery methods is taken up in the body in a similar way. Participants visit the study site regularly. During study visits, the doctors collect information about participants'…
Phase 1 • Sponsor: Boehringer Ingelheim • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC