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127005 trials found · Page 5688 of 6351
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Remote workouts tested for kids with cystic fibrosis
Symptom relief CompletedFitness in patients with Cystic fibrosis (CF) is an important biomarker associated with higher survivability and improved quality of life. CF patients are encouraged to maintain an active lifestyle, however, while physicians are able to prescribe airway clearance measures or spec…
Sponsor: MemorialCare Health System • Aim: Symptom relief
Last updated Aug 01, 2026 00:00 UTC
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Fatty liver after pancreatic cancer surgery linked to worse outcomes
Knowledge-focused CompletedWe will use simple summaries, educational handouts, and discussions with doctors and nurses to explain this study. The study looks at patients with early-stage pancreatic cancer who undergo pancreaticoduodenectomy (Whipple surgery). We found that some patients develop fatty liver…
Sponsor: Wei-Hsun Lu • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:52 UTC
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60,000 eyes tracked: scientists hunt genes behind cataract outcomes
Knowledge-focused Recruiting nowThe purpose of this study is to evaluate the long-term visual outcome of the cataract surgery using a large-scale and comprehensive database of high myopic cataract and age-related cataract patients. The investigators will further investigate into the various genetic and environm…
Sponsor: Shanghai High Myopia Study Group • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:32 UTC
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Vitamin D's hidden role in TB and fungal lung disease revealed
Knowledge-focused OngoingThe goal of the study is to determine whether vitamin D levels are associated with cytokine profiles in patients with pulmonary tuberculosis, including those with chronic pulmonary aspergillosis. The main questions it aims to answer are: * Is there an association between serum …
Sponsor: Research Institute of Epidemiology, Microbiology and Infectious Diseases, Uzbekistan • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:06 UTC
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Massive study aims to decode dental clues in rare diseases
Knowledge-focused Recruiting nowOroDental anomalies are one of the phenotypical aspects of at least 900 rare diseases or syndromes affecting by definition less than 1 in 2000 individual within the population (almost 25 million persons in Europe). They are often described in association with other organs or sys…
Sponsor: University Hospital, Strasbourg, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:34 UTC
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Gum treatment before heart surgery may save lives, study hints
Knowledge-focused CompletedThis retrospective observational study aims to evaluate the effect of preoperative periodontal treatment on postoperative infection and mortality in patients undergoing aortic and mitral valve surgery. Patient records between 2015 and 2024 analyzed. Demographic, clinical, and an…
Sponsor: Istanbul University - Cerrahpasa • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:03 UTC
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School lesson aims to help kids fight air pollution
Knowledge-focused OngoingThe BREATHE (Behavioral Research of Environment and Air Pollution Through Education) study is a pilot randomized control trial comparing the efficacy of a classroom-based intervention to no intervention in helping middle-school students understand and make behavioral decisions ab…
Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:03 UTC
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Younger age at cervical surgery may raise preterm birth risk
Knowledge-focused CompletedThe maternity ward attached to the colposcopy clinic was also the obstetrical referral center for the region and carried out approximately 2500 deliveries per year. The aim of the study was to assess whether an age younger than 25 years at conization affected future pregnancy out…
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Massive study reveals how neck and facial bleeding affects trauma victims
Knowledge-focused CompletedThis is a descriptive observational study of trauma patients admitted to the Trauma Unit at the Karolinska University Hospital Solna, Stockholm, Sweden. Data will be collected from the Karolinska Trauma Registry for all patients from 2015 to 2024. A more detailed dataset will be …
Sponsor: Karolinska University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC
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Blood protein may predict success after gastric bypass
Knowledge-focused CompletedThis study evaluated the prognostic value of preoperative pentraxin-3 (PTX3) levels in predicting weight loss, inflammatory resolution (CRP, IL-6), and metabolic improvements (HOMA-IR) following Roux-en-Y gastric bypass in patients with obesity.
Sponsor: Istanbul University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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Which scope is safer for kids? new study compares balloon enteroscopy methods
Diagnosis CompletedThe aim of our study was to compare the utility and safety of SBE and DBE in pediatric patients.
Sponsor: Shandong University • Aim: Diagnosis
Last updated Jun 27, 2026 09:05 UTC
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X-rays fall short: CT scans more accurate for ARDS diagnosis, study finds
Diagnosis CompletedThe presence of bilateral lung infiltrates on chest imaging is a mandatory criterion for the diagnosis of acute respiratory distress syndrome (ARDS). This retrospective single-center observational study assessed the agreement between chest radiograph interpreted by intensivists a…
Sponsor: Poitiers University Hospital • Aim: Diagnosis
Last updated Jun 27, 2026 09:03 UTC
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Can you deliver naturally after a C-Section? new study explores choices and outcomes
Knowledge-focused Completedin 2015 a protocol for trail of labor after a single cesarean delivery was approved by medical committee of Pescara Hospital. A database from outpatient clinic evaluated all women after 34 weeks' gestation with a previous cesarean delivery. Patients with a specific medical indica…
Sponsor: G. d'Annunzio University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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500 cancer patients help doctors see how radiation changes the body
Knowledge-focused Recruiting nowAnalysis to quantify intra-fraction, inter-fraction and post-treatment changes in tumor target volumes and surrounding normal organs in radiation therapy.
Sponsor: Medical College of Wisconsin • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Ice or cream? study tests cheaper pain relief for laser hair removal
Symptom relief OngoingThe primary objective of this study is to compare the efficacy of ice pack to topical eutectic mixture of local anesthesia (EMLA) for pain control in diode 810 nm laser axillary hair removal. This study is a pilot study designed to determine feasibility of these procedures.
Phase 4 • Sponsor: Northwestern University • Aim: Symptom relief
Last updated Jul 03, 2026 00:00 UTC
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Scientists probe inflammation clues in alcoholic liver disease
Knowledge-focused Recruiting nowThe main objective of this study is the comparison of the profile of the pro-inflammatory cytokines at the patients suffering from an alcoholic hepatitis to that of two groups witnesses: patients suffering from an alcoholic cirrhosis and unhurt patients of chronic liver disease
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:36 UTC
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15-Year study tracks hidden risks of gene therapy in children
Knowledge-focused By invitation onlyBackground: \- Gene therapy involves changing the genes inside the body s cells to stop disease. It is very closely regulated. People who have had this therapy may have problems months or even years later. Researchers do not know the long-term side effects, so they want to study…
Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated Jul 18, 2026 00:00 UTC
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Lung cancer drug interaction study seeks safer dosing
Knowledge-focused CompletedThis is a Phase I, open-label, 2-part study in patients with a confirmed diagnosis of epidermal growth factor receptor (EGFR) mutation positive (EGFRm+) non-small cell lung cancer (NSCLC), who have progressed following prior therapy with an approved EGFR tyrosine kinase inhibitor…
Phase 1 • Sponsor: AstraZeneca • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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Can your diet rewire your metabolism? scientists investigate
Knowledge-focused CompletedTo determine if consumption of different diet plans that both are nutritionally-adequate and provide energy to maintain body weight, alters fasting insulin concentrations, shifts other common clinical markers of metabolic disease risk, and affects metabolomic profiles that reflec…
Sponsor: USDA, Western Human Nutrition Research Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Scientists hunt for early warning signs of preterm birth
Knowledge-focused CompletedThe investigators project aims to identify, in pregnant women, discriminating molecules to allow an early detection of women who will spontaneously deliver prematurely, suitable in routine clinical practice. Human parturition is tightly correlated with hormonal changes at the ma…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC