Younger age at cervical surgery may raise preterm birth risk

NCT ID NCT05765188

Completed Knowledge-focused Sponsor: Centre Hospitalier Universitaire, Amiens Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether women who had a cervical procedure called LEEP (loop electrosurgical excision procedure) before age 25 face higher risks in future pregnancies, such as preterm labor or early rupture of membranes. Researchers reviewed records of 115 women who had LEEP and later gave birth, comparing those under 25 with those 25 or older at the time of the procedure. The goal is to see if younger age at conization is an independent factor for pregnancy complications.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: loop electrosurgical excision procedure (LEEP)
What this could lead to: If age at LEEP is found to be an independent risk factor, it could help doctors counsel younger women about future pregnancy risks.
What could go wrong: This is a small, retrospective study (115 women) that can only show associations, not cause and effect. Results may not apply to all populations.

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Conditions

The condition(s) this trial relates to.

Obstetric Labor, Premature pregnancy disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PREGNANCY COMPLICATIONS

Contacts and locations

Locations

CHU Amiens-Picardie

Amiens, 80054, France

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