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116076 trials found · Page 5547 of 5804
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Heart surgery study seeks best way to protect the heart
Knowledge-focused CompletedThe aim of the present study was to investigate intra-operative changes in markers of myocardial injury and myocardial intracellular amino acids during ischemia and reperfusion, comparing two methods of myocardial protection; Calafiore intermittent antegrade warm blood cardiopleg…
Sponsor: Damascus University • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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New device peers into brain during Parkinson's stimulation
Knowledge-focused CompletedThe purpose of this research is to test a new recorder that can measure brain activity when stimulation is turned on during deep brain stimulation (DBS) surgery. To continue to improve DBS therapy, the investigators need to better understand the changes in the brain of people wit…
Phase: NA • Sponsor: University of Minnesota • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC
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Video coaching boosts surgical skills for new doctors
Knowledge-focused OngoingSurgical coaching involves the development of a partnership between two surgeons in which one surgeon (coach) guides the other (coachee) in identifying goals, providing feedback and facilitating action planning. Surgical coaching provides an effective means of acquiring new techn…
Phase: NA • Sponsor: The Cleveland Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:06 UTC
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Tummy tuck upgrade? liposuction combo found safe in small trial
Knowledge-focused CompletedThis study evaluates the safety and outcomes of combining liposuction with varying degrees of abdominal flap undermining during abdominoplasty. Patients were randomly anssigned into three groups based on the extent of undermining and use of liposuction. Outcomes assessed included…
Phase: NA • Sponsor: Cairo University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:33 UTC
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New brain scanner peers into COVID's neurological mysteries
Knowledge-focused TerminatedThe primary goal of this project is to study the feasibility of a prototype brain-dedicated PET insert for an MR scanner for simultaneous acquisition of PET/MR images of metabolism and perfusion in Covid-19 negative and positive/once positive subjects. This study serves as a pilo…
Phase: NA • Sponsor: Stanford University • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC
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New piezosurgery method aims to reduce sinus lift complications
Knowledge-focused CompletedFor patients requiring LSFE, demographic data, including age, sex and smoking habits were collected. Preoperative CBCT images were analyzed for radiographic assessment of risk factors through measurement of sinus mucosa thickness, sinus lateral wall thickness, sinus width, presen…
Sponsor: Saint-Joseph University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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Nerve block may ease broken rib pain in emergency care
Symptom relief CompletedTo assess the feasibility and inform the design and conduct of a pragmatically conducted, interventional, multi-centre RCT in adult patients admitted to UK major trauma centres with rib fractures examining ESP block as an analgesic adjunct to existing multimodal analgesia in the …
Phase: NA • Sponsor: Nottingham University Hospitals NHS Trust • Aim: Symptom relief
Last updated Jun 27, 2026 12:00 UTC
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Hospital reviews thousands of surgeries to improve blood loss care
Knowledge-focused OngoingAfter review literature, Siriraj hospital has not unanimous protocol to guide proper preoperative anemia and blood transfusion. This retrospective study will review non-cardiac surgery cases and collect data such as demographic data, surgical procedures, anesthetic techniques, pr…
Sponsor: Siriraj Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:10 UTC
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Jumping for speed: 12 sessions of plyometric training may boost sprint in teens
Knowledge-focused CompletedThis field-based exploratory pre-post study examined the effects of a six-week horizontally oriented plyometric training program on sprint performance and sprint-related temporal-kinematic outcomes in early-adolescent male track-and-field athletes. Participants completed 12 super…
Phase: NA • Sponsor: Federal University of Vicosa • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Which graft works best for dental implants? new study compares options
Knowledge-focused CompletedThis prospective randomized clinical study evaluates and compares three different grafting approaches (allograft, xenograft, and combined grafting) used in lateral maxillary sinus augmentation prior to dental implant placement. Patients with posterior maxillary bone deficiency (…
Phase: NA • Sponsor: Tokat Gaziosmanpasa University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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Can a smartphone app make radiation treatment less confusing?
Knowledge-focused OngoingThis clinical trial determines how well the oncpatient mobile application work in assisting patients undergoing radiation treatment. Radiation therapy can be complex. The technology, daily treatments, and possible side effects can be confusing to prevent and manage. Traditional r…
Phase: NA • Sponsor: City of Hope Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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ADHD kids may be more prone to false memories, study suggests
Knowledge-focused CompletedThe purpose of the study is to test whether children with Attention Deficit/Hyperactivity Disorder (ADHD) are more susceptible to false memory production using a DRM paradigm. The number of "critical decoy production" errors will be analyzed and compared to the calibration of the…
Phase: NA • Sponsor: University Hospital, Angers • Aim: Knowledge-focused
Last updated Jun 26, 2026 19:11 UTC
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Immune cells linked to insulin resistance in new study
Knowledge-focused CompletedThis is a two-center proof-of-concept study, ancillary to the MetACTIV study, whose objective is to define immune activation profiles from the data of individuals followed by the Caisse Primaire d'Assurance Maladie du Gard (health insurance fund). The IRACTIV study will include …
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Can a breath test reveal how muscles make energy? tiny study explores new way to track treatment effects
Knowledge-focused CompletedPatients with metabolic myopathies suffer from exercise intolerance due to impaired ability to produce energy and secondary de-conditioning. There is a lack of methods enabling a non-invasive assessment of muscle energy production and studies regarding the benefits of therapeutic…
Phase: NA • Sponsor: University of British Columbia • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:02 UTC
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New stroke device trial halted early – too soon to tell
Disease control TerminatedThe study objective is to examine and compare clinical outcomes, as measured by Modified Rankin Scale (mRS) at 90 days (± 15 days) post treatment, and related performance characteristics of the Envi™-SR and concurrent parallel Control Devices currently cleared by the U.S. FDA for…
Phase: NA • Sponsor: NeuroVasc Technologies • Aim: Disease control
Last updated Jun 27, 2026 12:24 UTC
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Sleep study for infant hemangioma drug halted early
Symptom relief TerminatedThe purpose of this study is to assess the baseline sleep pattern disruption for patients starting oral propranolol at the standard BID dosing regimen compared to the control (timolol) group and to determine if there is a significant improvement in the sleep patterns in infants t…
Phase: PHASE4 • Sponsor: The University of Texas Health Science Center, Houston • Aim: Symptom relief
Last updated Jun 27, 2026 11:01 UTC
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New french tool aims to track arthritis drug adherence
Knowledge-focused Recruiting nowThe purpose of this study is to develop a French language version of the Compliance-Questionnaire-Rheumatology for use in French and Francophone rheumatology services
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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Can a sugar powder boost your immune system? UC davis study seeks answers
Knowledge-focused Recruiting nowTwo randomized double-blind placebo-controlled clinical studies to assess the effects of dietary glycan monomer supplementation on the immune system, especially antibody glycosylation in healthy adults. Immune profiling and glycoproteomics will be performed on serum isolated at t…
Phase: PHASE1 • Sponsor: University of California, Davis • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:39 UTC
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New study tests which dental filling lasts longest
Disease control CompletedEvaluating Two-year clinical performance of class I restored with four different flowable resin composite restorations.
Phase: NA • Sponsor: Mansoura University • Aim: Disease control
Last updated Jun 27, 2026 08:10 UTC
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Breathing experiment reveals how gas mixtures change heart function in healthy people
Knowledge-focused CompletedThe aim of the project is to evaluate the effect of hypercapnia on physiological parameters in a healthy person during short-term hypoxia and hypercapnia.
Phase: NA • Sponsor: Czech Technical University in Prague • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC