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127005 trials found · Page 5458 of 6351
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Can we predict which preemies will need a breathing tube?
Knowledge-focused CompletedNon-invasive respiratory support methods have been widely used in premature babies with respiratory distress syndrome (RDS) which has changed the basic management of premature babies in the early period. According to the 2019 European Guidelines on RDS management, early nasal CPA…
Sponsor: Ankara City Hospital Bilkent • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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Sniffing scents may ease hospital stress, small study suggests
Symptom relief CompletedThe purpose of this interventional study is to investigate the effects of aromatherapy on an acute care unit and whether it is effective in decreasing physical or emotional stressors that occur as a hospitalized patient. This study aimed to expand the limited literature on aromat…
Sponsor: University of California, Davis • Aim: Symptom relief
Last updated Jun 27, 2026 13:05 UTC
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Fitbit study tracks lung cancer Patients' steps to improve surgery recovery
Knowledge-focused Recruiting nowThis clinical trial evaluates the relationship between walking and sleeping habits and surgical outcomes in patients with lung cancer. Early walking after surgery is associated with decreased or less severe complications. Learning about how much patients walk may be important in …
Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:08 UTC
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New study aims to improve counseling for parents facing rare fetal tumor
Knowledge-focused CompletedSacrococcygeal teratoma (SCT) is the most common fetal and neonatal tumor. However, predicting factors of evolution, sequelae and relapse are still unreliable because of small-cohort studies. This study aims at identifying prenatal and postnatal prognostic factors of evolution of…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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COPD study aims to unlock secrets of lung health over time
Knowledge-focused CompletedThe intention with the study is to have a better understanding of what happens to COPD patients' symptoms, lung function and markers of inflammation over 12 weeks. This information will increase the understanding of COPD and how to design new treatments for COPD in the future.
Sponsor: AstraZeneca • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC
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Oxytocin's hidden power: pupil test reveals nervous system secrets
Knowledge-focused Stopped earlyThe purpose of this research is to evaluate the effects of oxytocin (naturally occurring hormone) given by an intramuscular (IM; into the muscle) injection, has on your parasympathetic nervous system. The parasympathetic nervous system is the part of the involuntary nervous syste…
Phase 2 • Sponsor: Wake Forest University Health Sciences • Aim: Knowledge-focused
Last updated Aug 30, 2026 00:00 UTC
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Small study explores how heart rhythm treatment affects brain function
Knowledge-focused CompletedCompare the difference of cognitive function between different treatment strategy in patients with persistent atrial fibrillation
Sponsor: National Taiwan University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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Can you train your body to handle pain better? new study investigates
Knowledge-focused CompletedThis project proposes to understand the sources of pain variability, and demonstrate that pain variability represents fluctuation in natural pain management. The project further proposes to determine if endogenous capacity to modulate pain can be trained to maximize their body's …
Sponsor: University of Florida • Aim: Knowledge-focused
Last updated Jul 02, 2026 00:00 UTC
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Mapping the immune System's fight against certain cancers
Knowledge-focused Recruiting nowThis is a correlative research project aimed at characterizing the T cell mediated immune responses to hepatocellular carcinoma (HCC), as well as Epstein-Barr virus (EBV)- and human papillomavirus (HPV)-related cancers. This study will enroll approximately 105 patients over 48 mo…
Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:04 UTC
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Heart surgery warning: thin vessel layer may predict deadly complications
Knowledge-focused Stopped earlyCardiac surgery has been described as altering endothelium structure and function, notably because of the use of cardiac-pulmonary bypass (CPB). Among the endothelial structure, glycocalyx, the thin layer recovering the endothelial surface, may be altered by the inflammatory proc…
Sponsor: University Hospital, Rouen • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC
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Experimental lung cancer vaccine trial halted early
Disease control Stopped earlyAn Open Label, Multi-Center, Dose Escalation/Expansion, Phase 1/1b Study of IMU 201 (PD1-Vaxx), a B-Cell Immunotherapy as monotherapy or in combination with atezolizumab with or without chemotherapy, in Adults with Non-Small Cell Lung Cancer (IMPrinter).
Phase 1 • Sponsor: Imugene Limited • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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Gene clue to worse eczema uncovered in new study
Knowledge-focused Recruiting nowThis protocol is primarily looking to see if the IL-4Ra R576 polymorphism is associated with increased clinical, immunological and microbial markers of disease activity in patients with Atopic dermatitis.
Sponsor: Boston Children's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:35 UTC
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Scientists decode how food and microbes shape Crohn's in kids
Knowledge-focused OngoingThe study is 3 arms observational study with no intervention that aims to understand the link between Crohn's disease, microbiome and diet in children. 150 children newly diagnosed with Crohn's disease will participate in the study and their data will be used to create an algori…
Sponsor: Weizmann Institute of Science • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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New camera could make cancer treatment safer by better tracking radiation
Knowledge-focused CompletedThe aim of this study is to assess the consistency between a dosimetry protocol using a large field of view CZT-camera and the dosimetry protocol used for recordings acquired with a conventional camera. Therefore, with the conventional camera, recordings are acquired on the "high…
Sponsor: Central Hospital, Nancy, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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Virtual reality could ease fear of shock therapy
Symptom relief CompletedLack of patient knowledge about ECT (electroconvulsive therapy) is a leading cause of treatment fear with 60% of ECT patients reporting high levels of anxiety. The purpose of this study is to determine if using Virtual Reality (VR) to allow patients' to experience a virtual ECT …
Sponsor: Sunnybrook Health Sciences Centre • Aim: Symptom relief
Last updated Aug 15, 2026 00:00 UTC
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Rouen hospital checks accuracy of COVID-19 antibody tests
Knowledge-focused Stopped earlyAt present, the offer of tests for the serological diagnosis of CoVID-19 (detection of IgG, IgM or IgA antibodies against CoV-2 SARS) is plethoric and is based on the use of a very large number of rapid diagnostic unit tests, a few dedicated high throughput automated systems or r…
Sponsor: University Hospital, Rouen • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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Could a yeast infection fuel endometriosis? new study investigates
Knowledge-focused CompletedEndometriosis is a chronic disease, of which the pathophysiology is still unknown. Several theories exist, the one of menstrual blood flow has been retained until now but does not fully explain it. The main symptoms are dysmenorrhea, dyspareunia and infertility. The aim of this s…
Sponsor: Centre Hospitalier Universitaire de la Guadeloupe • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
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Teens and parents share feelings on genetic risk results
Knowledge-focused CompletedThe Investigators will conduct a longitudinal, mixed-methods cohort study to assess primary and secondary psychosocial outcomes among MyCode adolescent participants and their parents, and health behaviors of children who received an adult- or pediatric-onset genomic result. Data …
Early phase 1 • Sponsor: Geisinger Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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Do drinks and drugs delay Life-Saving surgery? new study investigates
Knowledge-focused Recruiting nowThis prospective observational study aims to evaluate whether alcohol consumption, psychoactive drug use, or prior administration of analgesics affects the clinical evaluation and surgical decision-making process in patients with penetrating abdominal trauma. The study will be c…
Sponsor: Fundacion Clinica Valle del Lili • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC
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Yoga may ease breathing and boost daily life in bronchiectasis patients
Symptom relief CompletedEvaluation of the Effect of Yoga Training on Functional Capacity and Quality of Life in Patients with Bronchiectasis between the ages of 30-55
Sponsor: Istanbul Medipol University Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 07:57 UTC