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127005 trials found · Page 5353 of 6351
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New dialysis machine for tiny infants under study
Knowledge-focused By invitation onlyTo date, little knowledge exists related to the use of hemodialysis (HD) in infants and has been limited to mainly single center studies. The CARPEDIEM (CArdio-Renal PEdiatric Dialysis Emergency Machine) device, which can be used to provide hemodialysis in infants, has been launc…
Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Could a simple catheter cut nighttime bathroom trips and falls?
Symptom relief Recruiting nowThis is a single-center prospective pilot study of PureWick used as a management for nocturia and reduction of nighttime falls associated with going to the bathroom. Subjects are followed up to 3 months after the intervention. As a pilot study, it is expected that a 3-month follo…
Sponsor: Northwell Health • Aim: Symptom relief
Last updated Jun 27, 2026 14:00 UTC
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New device aims to improve diagnosis of voice disorders
Diagnosis OngoingThe objective of this registry is to confirm the safety and the performance of the ECE50 in medical routine by collecting data.
Sponsor: MED-EL Elektromedizinische Geräte GesmbH • Aim: Diagnosis
Last updated Jun 27, 2026 08:11 UTC
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Group therapy shows promise for borderline personality disorder
Symptom relief CompletedIn the context of therapy for Borderline Personality Disorder, our department had conduct a study titled "The Effectiveness of Dialectical Behavioral Group Psychotherapy Compared to Supportive Individual Psychotherapy in Patients with Borderline Personality Disorder: A Study of T…
Sponsor: Natalia Dewi Wardani, MD • Aim: Symptom relief
Last updated Jun 27, 2026 09:11 UTC
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UK doctors look back at real-world use of new VWD drug
Knowledge-focused CompletedThis study is a retrospective chart review study and will collect data on real world use of vonicog alfa (Recombinant Von Willebrand Factor \[rVWF\]). Von Willebrand disease (VWD) is the most common inherited bleeding disorder. rVWF is approved in Europe and UK to treat bleeding …
Sponsor: Takeda • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Radiation plus chemo for pancreatic cancer pain: trial ends early
Symptom relief Stopped earlyThe MASPAC trial investigates the added benefit of MR-guided adaptive SBRT of the primary tumor embedded between standard chemotherapy cycles for pain control and prevention of pain in patients with metastatic PDAC (mPDAC).
Phase 2 • Sponsor: Ludwig-Maximilians - University of Munich • Aim: Symptom relief
Last updated Jun 27, 2026 08:02 UTC
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Terpenes: the next frontier in pain relief?
Symptom relief OngoingThe purpose of this research is to assess the analgesic and subjective effects of terpenes administered alone and in combination of THC.
Phase 1 • Sponsor: University of California, Los Angeles • Aim: Symptom relief
Last updated Sep 10, 2026 00:00 UTC
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New drug 9MW1911 tested for safety in first human trial
Symptom relief CompletedThis study is a randomized, double-blind, dose-escalating phase I clinical study to evaluate the safety, tolerability and pharmacokinetics of 9MW1911 injection in healthy subjects.
Phase 1 • Sponsor: Mabwell (Shanghai) Bioscience Co., Ltd. • Aim: Symptom relief
Last updated Jun 27, 2026 08:04 UTC
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New PET scan agent could spot bladder cancer earlier
Diagnosis CompletedThe purpose of this study is to evaluate the use of 89Zr-labeled girentuximab (89Zr-TLX250) as a novel, carbonic anhydrase IX (CAIX) targeted PET/CT radiopharmaceutical for the imaging of Non-muscle-invasive bladder cancer (NMIBC) patients.
Early phase 1 • Sponsor: Institut Cancerologie de l'Ouest • Aim: Diagnosis
Last updated Jun 27, 2026 08:08 UTC
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Could a simple implant spare men from urinary pain after prostate radiation?
Symptom relief PausedMany patients may face long-term urinary side effects following stereotactic body radiation therapy (SBRT), including increased urinary frequency, dysuria, and nocturia. The investigator hypothesizes that Urolift, which represents a novel minimally invasive therapy, may reduce ac…
Sponsor: Northwell Health • Aim: Symptom relief
Last updated Jun 27, 2026 09:00 UTC
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Could a natural extract boost fertility treatment in PCOS?
Disease control Recruiting nowThe effect of combination therapy dlbs 3233 and clomifen citrate vs clomifen citrate on homa ir, maturation follicle, and menstrual cycle in PCOS cases at Muhammadiyah Asri Medical Center Hospital
Early phase 1 • Sponsor: Inlacinpenelitian • Aim: Disease control
Last updated Jun 27, 2026 09:04 UTC
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Study tests whether a friendly face in the delivery room eases labor pain
Symptom relief CompletedProblem Statement: In the governmental hospitals it is not allow to presence one of family with woman during child birth in labor room that affects negatively in pregnant emotion and feel more anxious especially primigravida although it effect positively in labor process and out…
Sponsor: The Hashemite University • Aim: Symptom relief
Last updated Jun 27, 2026 12:09 UTC
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New study follows 500 seniors with heart devices to improve care decisions
Knowledge-focused By invitation onlyThis is a prospective cohort study of older patients receiving implantable cardioverter-defibrillators. The purpose of the TRACER-ICD study is to conduct a prospective cohort investigation with the goal of 500 patients age \>65 receiving new primary prevention implantable cardiov…
Sponsor: Beth Israel Deaconess Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
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2000 myeloma patients to help shape future cancer care
Knowledge-focused Recruiting nowActually very few real life data are available for patients with multiple myeloma (MM), whereas they're playing a more and more important role in health care decisions. Treatments choice for medical care of patient with MM depends of their age, their general status, their eligibi…
Sponsor: University Hospital, Toulouse • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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Prolapse surgery showdown: which procedure wins?
Disease control OngoingThe purpose of this study is to compare two types of surgery for the treatment of uterovaginal prolapse to determine which surgery works best from a patient's perspective and has the lowest number of short-term and long-term complications.
Sponsor: University Hospitals Cleveland Medical Center • Aim: Disease control
Last updated Jun 27, 2026 12:33 UTC
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Ultrasound reveals hidden brain risks during aortic stent surgery
Knowledge-focused OngoingThis is an observational cohort study addressing the incidence of cerebral microemboli and alterations of cerebral hemodynamic physiology of the Relay®Branch thoracic stent-graft system.
Sponsor: University of Pennsylvania • Aim: Knowledge-focused
Last updated Jul 15, 2026 00:00 UTC
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Can your genes prevent bad drug reactions? new study aims to find out
Knowledge-focused Recruiting nowThe investigator's primary aim is to evaluate polypharmacy-associated adverse drug reactions (ADR) in a pilot study of at-risk patients using state-of-the-art pharmacogenomic technology and to use this information to make recommendations for optimization of pharmacotherapy regime…
Sponsor: Texas A&M University • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:34 UTC
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New software could spot dangerous aneurysm growth earlier
Knowledge-focused Recruiting nowThis is a Prospective Registry study to collect imaging and clinical data both on patients with aortic aneurysm disease undergoing serial monitoring and on patients pre and post-endovascular repair, using ViTAA (The Sponsor) aortic mapping technology.
Sponsor: ViTAA Medical Solutions • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:48 UTC
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Can a smartwatch replace doctor visits for cancer patients?
Knowledge-focused CompletedThis study investigates a device that closely monitors vital signs, as well as a smartphone application (app) that allows patients to respond to different questions and tests that will monitor for new symptoms. This study may help researchers understand if wearing the device is a…
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC
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New study checks if kidney disease affects cancer drug safety
Disease control Recruiting nowThis is a Phase 1b, multicenter, open-label, PK, and safety study of multiple oral doses of oral decitabine and cedazuridine (formerly known as ASTX727) as a fixed-dose combination of decitabine 35 milligrams (mg) and cedazuridine 100 mg in cancer participants with severe renal i…
Phase 1 • Sponsor: Taiho Oncology, Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:39 UTC